SCHEMBL783450

SCHEMBL783450

Brc1ccc2c(c1)C1(c3ccccc3-2)c2ccccc2-c2ccc(Br)cc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.58
PTPRC P08575 1/20 0.45
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
OPRK1 P41145 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
OPRM1 P35372 1/20 0.40
OPRD1 P41143 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP2A6 P11509 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
ALDH1A1 P00352 1/20 0.37
S100A4 P26447 2/20 0.37
AKR1A1 P14550 1/20 0.36
AKR1B1 P15121 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5846947 1.00 PDK2 (0.58) PDK2PTPRCKDM4EMAPTMEN1
SCHEMBL29574412 1.00 PDK2 (0.58) PDK2PTPRCKDM4EMAPTMEN1
SCHEMBL29602609 1.00 PDK2 (0.58) PDK2PTPRCKDM4EMAPTMEN1
SCHEMBL29399278 1.00 PDK2 (0.58) PDK2PTPRCKDM4EMAPTMEN1
SCHEMBL29397249 1.00 PDK2 (0.58) PDK2PTPRCKDM4EMAPTMEN1
SCHEMBL29511719 1.00 PDK2 (0.58) PDK2PTPRCKDM4EMAPTMEN1
SCHEMBL29530902 1.00 PDK2 (0.58) PDK2PTPRCKDM4EMAPTMEN1
SCHEMBL783463 1.00 PDK2 (0.58) PDK2PTPRCKDM4EMAPTMEN1
SCHEMBL996751 1.00 PDK2 (0.58) PDK2PTPRCKDM4EMAPTMEN1
SCHEMBL19164106 0.98 PDK2 (0.56) PDK2PTPRCKDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843933-A High free volume type polyarylpiperidine copolymer and anion exchange membrane 河北工业大学 2024-04-09 CN claimed
US-12528764-B2 Compound, coating composition comprising same, organic light-emitting device using same, and manufacturing method therefor LG CHEM, LTD. (KR) 2026-01-20 US disclosed
US-12389789-B2 Organic light emitting device LG CHEM, LTD. (KR) 2025-08-12 US disclosed
US-12378469-B2 Light emitting diode and condensed polycyclic compound for the same SAMSUNG DISPLAY CO., LTD. (KR) 2025-08-05 US disclosed
EP-3733732-B1 POLYPHENYLENE COMPOUND NISSAN CHEMICAL CORP (JP) 2025-03-26 EP disclosed
US-12252584-B2 Poly(aryl ether) based polymers and associated methods MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-03-18 US disclosed
US-20250017032-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE LIGHT EMITTING ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2025-01-09 US disclosed
US-20240213508-A1 FLUORINE-CONTAINING COMPOUND HAVING SULFONIC ACID GROUP AND POLYMER ELECTROLYTE FUEL CELL NISSAN CHEMICAL CORPORATION (JP) 2024-06-27 US disclosed
US-20240213508-A1 FLUORINE-CONTAINING COMPOUND HAVING SULFONIC ACID GROUP AND POLYMER ELECTROLYTE FUEL CELL NISSAN CHEMICAL CORPORATION (JP) 2024-06-27 US disclosed
US-11997921-B2 Organic light emitting device LG CHEM, LTD. (KR) 2024-05-28 US disclosed
EP-0935691-A1 OPTICAL BRIGHTENING AGENT Aventis Research & Technologies GmbH & Co. KG (DE) 1999-08-18 EP disclosed
WO-1999040655-A1 USE OF SPIRO COMPOUNDS AS LASER DYES AXIVA GMBH (DE) 1999-08-12 WO disclosed
EP-0882082-A1 PARTY CONJUGATED POLYMERS WITH SPIRO CENTRES AND THEIR USE AS ELECTRO-LUMINESCENT MATERIALS Hoechst Research & Technology Deutschland GmbH & Co. KG (DE) 1998-12-09 EP disclosed
US-5840217-A LIGHT-EMITTING, CHARGE-TRANSPORT, CHARGE-INJECTION MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1998-11-24 US disclosed
WO-1998042655-A1 SPIRO COMPOUNDS AND THE USE THEREOF AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 1998-10-01 WO disclosed
EP-0863931-A2 POLY(9,9'-SPIRO-BISFLUORENES), THE PRODUCTION AND USE OF SAME Ciba SC Holding AG (CH) 1998-09-16 EP disclosed
WO-1998018996-A1 OPTICAL BRIGHTENING AGENT AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 1998-05-07 WO disclosed
WO-1997031048-A1 PARTY CONJUGATED POLYMERS WITH SPIRO CENTRES AND THEIR USE AS ELECTRO-LUMINESCENT MATERIALS HOECHST RESEARCH & TECHNOLOGY DEUTSCHLAND GMBH & CO. KG (DE) 1997-08-28 WO disclosed
WO-1997020877-A2 POLY(9,9'-SPIRO-BISFLUORENES), THE PRODUCTION AND USE OF SAME CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-06-12 WO disclosed
EP-0676461-A2 Spiro compounds and their application as electroluminescence materials HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528764-B2 Compound, coating composition comprising same, organic light-emitting device using same, and manufacturing method therefor SEM1, CHRM1, ASH2L PDK2 3914/4885PTPRC 4753/4885KDM4E 1705/4885
US-12378469-B2 Light emitting diode and condensed polycyclic compound for the same SOD1, LIFR, NFE2L2 PDK2 387/4885PTPRC 1348/4885KDM4E 4078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.