Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.38 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12338161 | 0.84 | NR4A3 (0.66) | NR4A3RAB9ADRD2DRD4DRD3 | |
| SCHEMBL6534028 | 0.80 | NR4A3 (0.65) | NR4A3RAB9ADRD2DRD4DRD3 | |
| SCHEMBL18265951 | 0.74 | NR4A3 (0.61) | NR4A3RAB9ADRD2DRD4DRD3 | |
| SCHEMBL23401144 | 0.72 | NR4A3 (0.64) | NR4A3RAB9AMAPTALDH1A1NPSR1 | |
| SCHEMBL17610398 | 0.72 | NR4A3 (0.59) | NR4A3RAB9AMEN1KMT2ACYP2C19 | |
| SCHEMBL1906441 | 0.72 | NR4A3 (0.59) | NR4A3RAB9AMEN1KMT2AMAPT | |
| SCHEMBL4037627 | 0.72 | NR4A3 (0.59) | NR4A3RAB9AMAPTALDH1A1NPSR1 | |
| SCHEMBL12806554 | 0.70 | SMO (0.59) | NR4A3RAB9ADRD2DRD4DRD3 | |
| SCHEMBL12340468 | 0.70 | NR4A3 (0.56) | NR4A3RAB9AMEN1KMT2AMAPT | |
| SCHEMBL14468578 | 0.69 | NR4A3 (0.51) | NR4A3RAB9ADRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308838-B1 | NITROGEN-CONTAINING AROMATIC HETEROCYCLYL COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2016-02-17 | — | — | EP | disclosed |