Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A3 | Q92570 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12338161 | 0.88 | NR4A3 (0.66) | NR4A3ALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL26042 | 0.87 | NR4A3 (0.54) | NR4A3ALDH1A1MAPK1RAB9AMAPT | |
| SCHEMBL6533834 | 0.81 | NPBWR1 (0.52) | NR4A3ALDH1A1RAB9ANPC1NPSR1 | |
| SCHEMBL17533976 | 0.80 | NR4A3 (0.52) | NR4A3ALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL23401144 | 0.79 | NR4A3 (0.64) | NR4A3ALDH1A1MAPK1HPGDRAB9A | |
| SCHEMBL1568047 | 0.79 | SMO (0.57) | NR4A3ALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL1905624 | 0.79 | NR4A3 (1.00) | NR4A3ALDH1A1MAPK1HPGDRAB9A | |
| SCHEMBL18265951 | 0.77 | NR4A3 (0.61) | NR4A3ALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL1906441 | 0.76 | NR4A3 (0.59) | NR4A3ALDH1A1MAPK1HPGDRAB9A | |
| SCHEMBL23399486 | 0.76 | NR4A3 (0.55) | NR4A3ALDH1A1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |