Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12484179 | 0.85 | HRH3 (0.92) | HRH3 | |
| Suvn-G3031 SCHEMBL12484542 | 0.84 | HRH3 (1.00) | HRH3 | |
| SCHEMBL15674505 | 0.84 | HRH3 (1.00) | HRH3ALDH1A1HPGDALOX15KDM4E | |
| SCHEMBL12484492 | 0.84 | HRH3 (1.00) | HRH3 | |
| Suvn-G3031 SCHEMBL12486477 | 0.83 | HRH3 (1.00) | HRH3 | |
| Suvn-G3031 SCHEMBL22186742 | 0.82 | HRH3 (0.98) | HRH3 | |
| Cadaverine Tartrate SCHEMBL19876799 | 0.79 | HRH3 (0.80) | HRH3 | |
| SCHEMBL29114487 | 0.79 | HRH3 (0.74) | HRH3ALDH1A1HPGDALOX15 | |
| Cadaverine Tartrate SCHEMBL20996298 | 0.79 | HRH3 (0.89) | HRH3ALDH1A1HPGDALOX15KDM4E | |
| SCHEMBL8799456 | 0.78 | HRH3 (0.49) | HRH3HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027275-A1 | PROCESS FOR LARGE SCALE PRODUCTION OF N-[4-(1- CYCLOBUTYL PIPERIDIN-4-YLOXY) PHENYL]-2-(MORPHOLIN-4-YL) ACET AMIDE DIHYDROCHLORIDE | SUVEN LIFE SCIENCES LIMITED (IN) | 2016-02-25 | — | — | WO | disclosed |