Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.32 |
| ▸ | KDM5A | P29375 | 4/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14016289 | 0.85 | — | — | |
| SCHEMBL17535271 | 0.84 | GGPS1 (0.35) | DNM1GGPS1FDPSAGTR1OPRM1 | |
| SCHEMBL9284234 | 0.80 | DNM1 (0.36) | DNM1GGPS1FDPSAGTR1OPRM1 | |
| SCHEMBL22109500 | 0.79 | GGPS1 (0.39) | DNM1GGPS1FDPSAGTR1OPRM1 | |
| SCHEMBL20246651 | 0.79 | — | — | |
| SCHEMBL24385090 | 0.76 | MAPT (0.38) | — | |
| SCHEMBL23073620 | 0.76 | TSHR (0.32) | — | |
| SCHEMBL17092834 | 0.76 | GGPS1 (0.40) | DNM1GGPS1FDPSAGTR1OPRM1 | |
| SCHEMBL24429079 | 0.74 | DNM1 (0.32) | DNM1GGPS1FDPSAGTR1OPRM1 | |
| SCHEMBL25096697 | 0.74 | CA12 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188272-B1 | PHENYL- AND BENZYLTHIAZOLYLPIPERAZINE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | REMYND NV (BE) | 2016-02-24 | — | — | EP | disclosed |