Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17535604 | 1.00 | ALDH1A1 (0.40) | ALDH1A1KMT2ASTAT3CYP2D6CYP1A2 | |
| SCHEMBL14972291 | 1.00 | ALDH1A1 (0.40) | ALDH1A1KMT2ASTAT3CYP2D6CYP1A2 | |
| SCHEMBL23989830 | 0.86 | ALDH1A1 (0.38) | ALDH1A1KMT2ASTAT3CYP2D6CYP1A2 | |
| SCHEMBL20014121 | 0.86 | STAT3 (0.39) | ALDH1A1KMT2ASTAT3CYP2D6CYP1A2 | |
| SCHEMBL30030113 | 0.86 | ALDH1A1 (0.38) | ALDH1A1KMT2ASTAT3CYP2D6CYP1A2 | |
| SCHEMBL30565480 | 0.86 | STAT3 (0.39) | ALDH1A1KMT2ASTAT3CYP2D6CYP1A2 | |
| SCHEMBL15348113 | 0.84 | CA12 (0.39) | ALDH1A1KMT2ASTAT3CYP2D6CYP1A2 | |
| SCHEMBL20014131 | 0.84 | KMT2A (0.40) | ALDH1A1KMT2ASTAT3CYP2D6CYP1A2 | |
| SCHEMBL2304680 | 0.83 | STAT3 (0.38) | ALDH1A1KMT2ASTAT3CYP2D6CYP1A2 | |
| SCHEMBL32680542 | 0.81 | ESR1 (0.41) | ALDH1A1KMT2ASTAT3CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064223-A1 | TRI-SUBSTITUTED PYRIDINES | GOSSAMER BIO SERVICES, INC. (US) | 2023-04-20 | — | — | WO | disclosed |
| EP-2970331-B1 | SPIRO AZETIDINE ISOXAZOLE DERIVATIVES AND THEIR USE AS SSTR5 ANTAGONISTS | TAKEDA PHARMACEUTICALS CO (JP) | 2017-05-17 | — | — | EP | disclosed |
| US-9605000-B2 | Spiro azetidine isoxazole derivatives and their use as SSTR antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-03-28 | — | — | US | disclosed |
| US-20160060273-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060273-A1 | HETEROCYCLIC COMPOUND | SSTR5, SSTR1, SSTR2 | ALDH1A1 2449/4885KMT2A 2455/4885STAT3 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.