Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.34 |
| ▸ | ANPEP | P15144 | 3/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.33 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1512978 | 1.00 | GRIK1 (0.36) | GRIK1GRIK2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1512949 | 0.84 | ACE (0.36) | GRIK1GRIK2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL16360436 | 0.75 | ANPEP (0.57) | ANPEP | |
| SCHEMBL28380252 | 0.74 | ANPEP (0.56) | GRIK1GRIK2ANPEPERAP2 | |
| SCHEMBL28380251 | 0.74 | ANPEP (0.56) | GRIK1GRIK2ANPEPERAP2 | |
| SCHEMBL901643 | 0.74 | ALDH1A1 (0.33) | SLC6A3 | |
| SCHEMBL343088 | 0.74 | ALDH1A1 (0.33) | SLC6A3 | |
| SCHEMBL2534066 | 0.73 | HTT (0.35) | — | |
| SCHEMBL936034 | 0.71 | GRIN2D (0.43) | GRIK1GRIK2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL14844482 | 0.71 | METAP1 (0.43) | GRIK1GRIK2GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010147464-A1 | USE OF A CYSTEINE SYNTHESIZING ENZYME AS SELECTABLE MARKER | CELLAGENICS B.V. (NL) | 2010-12-23 | — | — | WO | claimed |
| US-10106799-B2 | Stringent selectable markers | CELLAGENICS B.V. (NL) | 2018-10-23 | — | — | US | disclosed |
| US-9650630-B2 | Nucleic acid fragments from a ribosomal protein promoter for enhancing gene expression | CELLAGENICS B.V. (NL) | 2017-05-16 | — | — | US | disclosed |
| US-20160160221-A1 | NOVEL STRINGENT SELECTABLE MARKERS | CELLAGENICS B.V. (NL) | 2016-06-09 | — | — | US | disclosed |
| US-9284563-B2 | Stringent selectable markers | CELLAGENICS B.V. (NL) | 2016-03-15 | — | — | US | disclosed |
| CN-103180443-B | For the nucleic acid fragment from ribosomal protein promotor of reinforcing gene expression | CELLAGENICS B.V. (NL) | 2016-01-13 | — | — | CN | disclosed |
| EP-2443239-B1 | NOVEL STRINGENT SELECTABLE MARKERS | CELLAGENICS B V (NL) | 2015-11-25 | — | — | EP | disclosed |
| EP-2611915-B1 | NUCLEIC ACID FRAGMENTS FROM A RIBOSOMAL PROTEIN PROMOTER FOR ENHANCING GENE EXPRESSION | CELLAGENICS B V (NL) | 2015-04-15 | — | — | EP | disclosed |
| US-20130236956-A1 | NUCLEIC ACID FRAGMENTS FROM A RIBOSOMAL PROTEIN PROMOTER FOR ENHANCING GENE EXPRESSION | CELLAGENICS B.V. | 2013-09-12 | — | — | US | disclosed |
| EP-2611915-A1 | NUCLEIC ACID FRAGMENTS FROM A RIBOSOMAL PROTEIN PROMOTER FOR ENHANCING GENE EXPRESSION | Cellagenics B.V. (NL) | 2013-07-10 | — | — | EP | disclosed |
| CN-103180443-A | Nucleic acid fragments from a ribosomal protein promoter for enhancing gene expression | CELLAGENICS B V | 2013-06-26 | — | — | CN | disclosed |
| US-20120156672-A1 | NOVEL STRINGENT SELECTABLE MARKERS | Cella Genics B.V. | 2012-06-21 | — | — | US | disclosed |
| EP-2443239-A2 | NOVEL STRINGENT SELECTABLE MARKERS | Cellagenics B.V. (NL) | 2012-04-25 | — | — | EP | disclosed |
| WO-2012030218-A1 | NUCLEIC ACID FRAGMENTS FROM A RIBOSOMAL PROTEIN PROMOTER FOR ENHANCING GENE EXPRESSION | CELLAGENICS B.V. (NL) | 2012-03-08 | — | — | WO | disclosed |
| WO-2010147464-A1 | USE OF A CYSTEINE SYNTHESIZING ENZYME AS SELECTABLE MARKER | CELLAGENICS B.V. (NL) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010147462-A2 | NOVEL STRINGENT SELECTABLE MARKERS | CELLAGENICS B.V. (NL) | 2010-12-23 | — | — | WO | disclosed |