Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | PPARG | P37231 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15237117 | 0.94 | ALDH1A1 (0.61) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL10459923 | 0.86 | ALDH1A1 (0.74) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL16521907 | 0.86 | ALDH1A1 (0.58) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL19651993 | 0.86 | ALDH1A1 (0.58) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL2832966 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL14225533 | 0.84 | ALDH1A1 (0.60) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL15835600 | 0.84 | TSHR (0.69) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL15934083 | 0.84 | ALDH1A1 (0.90) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL13181791 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL12440176 | 0.83 | ALDH1A1 (1.00) | ALDH1A1TP53TSHRMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8444899-B2 | Methods and materials for fabricating microfluidic devices | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120256354-A1 | METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-10-11 | — | — | US | disclosed |
| US-8158728-B2 | Methods and materials for fabricating microfluidic devices | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-04-17 | — | — | US | disclosed |
| US-20090281250-A1 | METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-11-12 | — | — | US | disclosed |