Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.38 |
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11942794 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRCES2CES1RECQL | |
| SCHEMBL13171272 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRCES2CES1RECQL | |
| SCHEMBL15695434 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRCES2CES1RECQL | |
| SCHEMBL16746068 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRCES2CES1RECQL | |
| SCHEMBL13559119 | 0.91 | ALDH1A1 (0.45) | ALDH1A1TSHRCES2CES1RECQL | |
| SCHEMBL16882974 | 0.86 | ALDH1A1 (0.42) | ALDH1A1TSHRCES2CES1 | |
| SCHEMBL92114 | 0.82 | — | — | |
| SCHEMBL12697091 | 0.82 | CES1 (0.48) | ALDH1A1TSHRCES2CES1LMNA | |
| SCHEMBL7622214 | 0.81 | LPAR3 (0.53) | ALDH1A1 | |
| SCHEMBL17977194 | 0.81 | LPAR3 (0.53) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9662809-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160236379-A1 | Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2016-08-18 | — | — | US | disclosed |
| US-9340001-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-20150101743-A1 | Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2015-04-16 | — | — | US | disclosed |
| US-8662878-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2014-03-04 | — | — | US | disclosed |
| US-20130228950-A1 | METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-09-05 | — | — | US | disclosed |
| US-20130202729-A1 | Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| US-8158728-B2 | Methods and materials for fabricating microfluidic devices | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-04-17 | — | — | US | disclosed |
| US-20090281250-A1 | METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-11-12 | — | — | US | disclosed |