⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20119618 | 0.80 | LMNA (0.33) | — | |
| SCHEMBL11400000 | 0.80 | — | — | |
| SCHEMBL841687 | 0.80 | — | — | |
| SCHEMBL14738349 | 0.80 | — | — | |
| SCHEMBL1639903 | 0.80 | — | — | |
| SCHEMBL9963716 | 0.78 | — | — | |
| SCHEMBL24050466 | 0.77 | NPC1 (0.34) | — | |
| SCHEMBL19601418 | 0.77 | — | — | |
| SCHEMBL19608177 | 0.75 | — | — | |
| SCHEMBL22096764 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 793 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612409-B2 | Pyrrolopyrimidines as CFTR potentiators | CYSTIC FIBROSIS FOUNDATION (US) | 2026-04-28 | — | — | US | disclosed |
| US-12552765-B2 | Small molecule modulators of pantothenate kinases | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 2026-02-17 | — | — | US | disclosed |
| US-12552755-B2 | Cinnamic amide derivative having FXR activating effect, pharmaceutical composition containing the same as active ingredient, and method for preparing the same | KYUNGSUNG UNIVERSITY INDUSTRY COOPERATION FOUNDATION (KR) | 2026-02-17 | — | — | US | disclosed |
| EP-3731859-B1 | PYRIDAZINE COMPOUNDS FOR USE TO TREAT DISORDERS ASSOCIATED WITH CASTOR | ST JUDE CHILDRENS RES HOSPITAL INC (US) | 2025-08-20 | — | — | EP | disclosed |
| US-20250090526-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 2025-03-20 | — | — | US | disclosed |
| US-12202826-B2 | N-pyridinyl acetamide derivatives as inhibitors of the Wnt signaling pathway | REDX PHARMA PLC (GB) | 2025-01-21 | — | — | US | disclosed |
| US-12194031-B2 | Compounds for use in regulating follicle maturation | AARHUS UNIVERSITET (DK) | 2025-01-14 | — | — | US | disclosed |
| US-20250002487-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2025-01-02 | — | — | US | disclosed |
| CN-111787939-B | Methods of treating CASTOR-related disorders | 圣朱德儿童研究医院有限公司 | 2024-09-13 | — | — | CN | disclosed |
| US-20240239811-A1 | 5-(5-(PIPERIDIN-4-YL)THIENO[3,2-C]PYRAZOL-2-YL]INDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE T | REMIX THERAPEUTICS INC. | 2024-07-18 | — | — | US | disclosed |
| US-20070135631-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-06-14 | — | — | US | disclosed |
| US-20070082908-A1 | Bicycle pyrazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-12 | — | — | US | disclosed |
| US-20070082908-A1 | Bicycle pyrazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-12 | — | — | US | disclosed |
| US-20070049603-A1 | Raf inhibitor compounds and methods of use thereof | ARRAY BIOPHARMA INC. | 2007-03-01 | — | — | US | disclosed |
| US-7163951-B2 | N-biarylmethyl aminocycloalkanecarboxamide derivatives | MERCK & CO., INC. (US) | 2007-01-16 | — | — | US | disclosed |
| US-7157476-B2 | Aminofurazan compounds useful as protein kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-01-02 | — | — | US | disclosed |
| EP-0046193-B1 | 1-HYDROXYPYRAZOLE AND PROCESS FOR PREPARING THE SAME | BASF Aktiengesellschaft (DE) | 1983-09-28 | — | — | EP | disclosed |
| US-4350819-A | 1-Hydroxypyrazole | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |
| US-4337188-A | POLYMERIC BLENDS FOR PACKAGING | DU PONT CANADA INC. (CA) | 1982-06-29 | — | — | US | disclosed |
| EP-0046193-A1 | 1-Hydroxypyrazole and process for preparing the same | BASF Aktiengesellschaft (DE) | 1982-02-24 | — | — | EP | disclosed |