Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875592 | 0.83 | PDE4A (0.54) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL13010838 | 0.82 | KDM4E (0.47) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL13010836 | 0.82 | KDM4E (0.47) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL9235255 | 0.82 | LMNA (0.44) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| Mannitol SCHEMBL8472459 | 0.77 | LMNA (0.69) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| Mannitol SCHEMBL11031577 | 0.77 | LMNA (0.69) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| Mannitol SCHEMBL26606265 | 0.77 | LMNA (0.69) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| Mannitol SCHEMBL7927609 | 0.77 | LMNA (0.69) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| Mannitol SCHEMBL3017327 | 0.77 | LMNA (0.69) | KDM4ELMNAL3MBTL1TDP1PDE4A | |
| Mannitol SCHEMBL21903806 | 0.74 | LMNA (0.65) | KDM4ELMNAL3MBTL1TDP1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2995604-B1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN) | 2019-07-10 | — | — | EP | disclosed |
| US-9517988-B2 | Phenol derivative and preparation method and use in medicine thereof | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2016-12-13 | — | — | US | disclosed |
| EP-2995604-A1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2016-03-16 | — | — | EP | disclosed |
| US-20160060197-A1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060197-A1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | CYP2D6, CYP2B6, CYP2A6 | KDM4E 1414/4885LMNA 2674/4885L3MBTL1 4412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.