SCHEMBL17537488

SCHEMBL17537488

O=P(O)(C[P@@](=O)(O)c1ccccc1)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.73
CA2 P00918 1/20 0.59
CA4 P22748 1/20 0.59
CA5A P35218 1/20 0.59
ALDH1A1 P00352 3/20 0.55
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
GAA P10253 2/20 0.48
TSHR P16473 2/20 0.48
ALOX15 P16050 1/20 0.48
USP2 O75604 1/20 0.48
PTPN2 P17706 3/20 0.47
PTPN1 P18031 3/20 0.47
PTPN4 P29074 3/20 0.47
PTPN9 P43378 3/20 0.47
PTPN11 Q06124 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17488976 1.00 CFTR (0.73) CFTRCA2CA4CA5AALDH1A1
SCHEMBL806049 0.84 CFTR (1.00) CFTRCA2CA4CA5AALDH1A1
SCHEMBL6549541 0.82 CFTR (0.70) CFTRCA2CA4CA5AALDH1A1
SCHEMBL28106722 0.82 CFTR (0.70) CFTRCA2CA4CA5AALDH1A1
SCHEMBL31331654 0.80 CFTR (0.67) CFTRCA2CA4CA5AALDH1A1
SCHEMBL28485753 0.80 CFTR (0.67) CFTRCA2CA4CA5AALDH1A1
SCHEMBL5668125 0.80 CFTR (0.67) CFTRCA2CA4CA5AALDH1A1
SCHEMBL21642988 0.80 CFTR (0.67) CFTRCA2CA4CA5AALDH1A1
SCHEMBL14287997 0.80 CFTR (0.82) CFTRCA2CA4CA5AALDH1A1
SCHEMBL575313 0.80 CFTR (0.67) CFTRCA2CA4CA5AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9826129-B2 Near-infrared-ray-absorbing composition, near-infrared-ray cut filter using same, manufacturing method therefor, camera module, and manufacturing method therefor FUJIFILM CORPORATION (JP) 2017-11-21 US disclosed
US-9826129-B2 Near-infrared-ray-absorbing composition, near-infrared-ray cut filter using same, manufacturing method therefor, camera module, and manufacturing method therefor FUJIFILM CORPORATION (JP) 2017-11-21 US disclosed
EP-2985639-A1 NEAR-INFRARED-RAY-ABSORBING COMPOSITION, NEAR-INFRARED-RAY CUT FILTER USING SAME, MANUFACTURING METHOD THEREFOR, CAMERA MODULE, AND MANUFACTURING METHOD THEREFOR Fujifilm Corporation (JP) 2016-02-17 EP disclosed
US-20160037034-A1 NEAR-INFRARED-RAY-ABSORBING COMPOSITION, NEAR-INFRARED-RAY CUT FILTER USING SAME, MANUFACTURING METHOD THEREFOR, CAMERA MODULE, AND MANUFACTURING METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-02-04 US disclosed
US-20160037034-A1 NEAR-INFRARED-RAY-ABSORBING COMPOSITION, NEAR-INFRARED-RAY CUT FILTER USING SAME, MANUFACTURING METHOD THEREFOR, CAMERA MODULE, AND MANUFACTURING METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160037034-A1 NEAR-INFRARED-RAY-ABSORBING COMPOSITION, NEAR-INFRARED-RAY CUT FILTER USING SAME, MANUFACTURING METHOD THEREFOR, CAMERA MODULE, AND MANUFACTURING METHOD THEREFOR FAR1, SLC39A11, NOTUM CFTR 1565/4885CA2 4129/4885CA4 1534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.