SCHEMBL17538366

SCHEMBL17538366

Cc1cc(C#N)cc2nc(-c3ccc(CCCOC4CCCCCC4)cc3)oc12

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CETP P11597 19/20 0.53
CEPT1 Q9Y6K0 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1734867 0.88 CETP (0.52) CETP
SCHEMBL12153078 0.82 CETP (0.49) CETP
SCHEMBL1734704 0.80 CETP (0.58) CETPCEPT1
SCHEMBL1734837 0.79 CETP (0.57) CETPCEPT1
SCHEMBL13677317 0.79 CETP (0.57) CETPCEPT1
SCHEMBL13677228 0.78 CETP (0.49) CETP
SCHEMBL12153066 0.76 CETP (0.49) CETPCEPT1
SCHEMBL1735003 0.72 CETP (0.51) CETPCEPT1
SCHEMBL1735100 0.72 CEPT1 (0.53) CETPCEPT1
SCHEMBL1733972 0.72 CEPT1 (0.53) CETPCEPT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1954287-B2 CETP INHIBITORS MERCK SHARP & DOHME (US) 2016-02-24 EP disclosed