Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.66 |
| ▸ | ERBB2 | P04626 | 9/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17538500 | 0.92 | EGFR (0.69) | EGFRERBB2 | |
| SCHEMBL17538482 | 0.85 | EGFR (0.81) | EGFRERBB2 | |
| SCHEMBL17538486 | 0.84 | EGFR (0.85) | EGFRERBB2 | |
| SCHEMBL17538476 | 0.83 | EGFR (0.81) | EGFRERBB2 | |
| SCHEMBL17538504 | 0.82 | EGFR (0.83) | EGFRERBB2 | |
| SCHEMBL17498519 | 0.81 | EGFR (0.83) | EGFRERBB2 | |
| SCHEMBL16405547 | 0.81 | EGFR (0.83) | EGFRERBB2 | |
| SCHEMBL20325513 | 0.81 | EGFR (0.84) | EGFRERBB2 | |
| SCHEMBL17538507 | 0.79 | EGFR (0.87) | EGFRERBB2 | |
| SCHEMBL19027000 | 0.78 | EGFR (0.58) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016023217-A1 | QUINAZOLINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 安润医药科技（苏州）有限公司 | 2016-02-18 | — | — | WO | disclosed |