Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.58 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19026591 | 0.90 | EGFR (0.59) | EGFRERBB2 | |
| SCHEMBL19027150 | 0.89 | EGFR (0.60) | EGFRERBB2FBP1KDR | |
| SCHEMBL19026693 | 0.88 | EGFR (0.74) | EGFRERBB2FBP1KDR | |
| SCHEMBL17538482 | 0.83 | EGFR (0.81) | EGFRERBB2 | |
| SCHEMBL17538500 | 0.81 | EGFR (0.69) | EGFRERBB2 | |
| SCHEMBL17538476 | 0.80 | EGFR (0.81) | EGFRERBB2 | |
| SCHEMBL18632967 | 0.79 | FBP1 (0.76) | EGFRERBB2FBP1KDR | |
| SCHEMBL17538501 | 0.78 | EGFR (0.66) | EGFRERBB2 | |
| SCHEMBL19125553 | 0.77 | EGFR (0.63) | EGFRERBB2FBP1KDR | |
| SCHEMBL18979196 | 0.76 | EGFR (0.69) | EGFRERBB2FBP1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181553-A1 | QUINAZOLINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Arromax Pharmatech Co., Ltd. (CN) | 2017-06-21 | — | — | EP | disclosed |