SCHEMBL17540440

SCHEMBL17540440

CCn1c2ccccc2c2cc(C(=O)/C(CCC3CCCCC3)=N/OC(C)=O)ccc21

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.46
KDM4E B2RXH2 2/20 0.46
LMNA P02545 2/20 0.46
MAPT P10636 1/20 0.46
PTGER4 P35408 4/20 0.43
RORC P51449 2/20 0.43
CNR2 P34972 4/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
REV1 Q9UBZ9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17540436 0.91 NPC1 (0.45) NPC1KDM4ELMNAMAPTPTGER4
SCHEMBL17540437 0.89 NPC1 (0.48) NPC1KDM4ELMNAMAPTPTGER4
SCHEMBL17540434 0.89 CNR2 (0.44) NPC1KDM4ELMNAMAPTCNR2
SCHEMBL17540443 0.86 PTGER4 (0.47) KDM4ELMNAMAPTPTGER4CNR2
SCHEMBL17540435 0.85 CNR2 (0.40) NPC1KDM4ELMNAMAPTPTGER4
SCHEMBL20015388 0.83 CNR2 (0.35) NPC1KDM4ELMNAMAPTPTGER4
SCHEMBL21898018 0.83 CNR2 (0.38) NPC1KDM4ERORCCNR2
SCHEMBL31099279 0.83 CNR2 (0.38) NPC1KDM4ERORCCNR2
SCHEMBL28936992 0.83 CNR2 (0.38) NPC1KDM4ERORCCNR2
SCHEMBL13863496 0.82 KDM4E (0.50) NPC1KDM4ELMNAMAPTCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9383480-B2 Photocurable acrylate composition CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-07-05 US disclosed
US-9383480-B2 Photocurable acrylate composition CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-07-05 US disclosed
EP-3002632-A1 ACRYLIC PHOTOCURABLE COMPOSITION Changzhou Tronly Advanced Electronics Materials Co., Ltd. (CN) 2016-04-06 EP disclosed
US-20160047945-A1 PHOTOCURABLE ACRYLATE COMPOSITION CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-02-18 US disclosed
US-20160047945-A1 PHOTOCURABLE ACRYLATE COMPOSITION CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-02-18 US disclosed