SCHEMBL17540437

SCHEMBL17540437

CCn1c2ccccc2c2cc(/C(CCC3CCCCC3)=N/OC(C)=O)ccc21

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.48
KDM4E B2RXH2 3/20 0.47
LMNA P02545 3/20 0.47
MAPT P10636 2/20 0.47
PTGER4 P35408 3/20 0.44
RORC P51449 2/20 0.44
CNR2 P34972 5/20 0.42
POLB P06746 1/20 0.42
MAPK1 P28482 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 1/20 0.42
REV1 Q9UBZ9 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CNR1 P21554 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19439766 0.92 CNR2 (0.42) NPC1KDM4ELMNAMAPTPTGER4
SCHEMBL17540420 0.91 NPC1 (0.46) NPC1KDM4ELMNAMAPTPTGER4
SCHEMBL17540440 0.89 NPC1 (0.46) NPC1KDM4ELMNAMAPTPTGER4
SCHEMBL20653027 0.88 CNR2 (0.39) NPC1KDM4ELMNAMAPTPTGER4
SCHEMBL23552994 0.88 CNR2 (0.47) NPC1KDM4ELMNAMAPTPTGER4
SCHEMBL21253182 0.88 KMT2A (0.38) NPC1KDM4ELMNAMAPTPTGER4
SCHEMBL31650942 0.88 KMT2A (0.38) NPC1KDM4ELMNAMAPTPTGER4
SCHEMBL19632436 0.88 KMT2A (0.38) NPC1KDM4ELMNAMAPTPTGER4
SCHEMBL16548356 0.88 KMT2A (0.38) NPC1KDM4ELMNAMAPTPTGER4
SCHEMBL29378382 0.88 KMT2A (0.38) NPC1KDM4ELMNAMAPTPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11054743-B2 Fluorene polyfunctional photoinitiator and preparation and use thereof, and photosensitive resin composition containing fluorene photoinitiator and use thereof CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2021-07-06 US disclosed
EP-3392232-B1 FLUORENE MULTIFUNCTIONAL PHOTOINITIATOR AND PREPARATION AND USE THEREOF, AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING FLUORENE PHOTOINITIATOR AND USE THEREOF CHANGZHOU TRONLY ADVANCED ELECTRONIC MAT CO LTD (CN) 2021-02-17 EP disclosed
US-20200264508-A1 FLUORENE POLYFUNCTIONAL PHOTOINITIATOR AND PREPARATION AND USE THEREOF, AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING FLUORENE PHOTOINITIATOR AND USE THEREOF CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2020-08-20 US disclosed
EP-3002632-B1 ACRYLIC PHOTOCURABLE COMPOSITION CHANGZHOU TRONLY ADVANCED ELECTRONICS MAT CO LTD (CN) 2018-03-28 EP disclosed
US-9383480-B2 Photocurable acrylate composition CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-07-05 US disclosed
US-9383480-B2 Photocurable acrylate composition CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-07-05 US disclosed
EP-3002632-A1 ACRYLIC PHOTOCURABLE COMPOSITION Changzhou Tronly Advanced Electronics Materials Co., Ltd. (CN) 2016-04-06 EP disclosed
US-20160047945-A1 PHOTOCURABLE ACRYLATE COMPOSITION CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-02-18 US disclosed
US-20160047945-A1 PHOTOCURABLE ACRYLATE COMPOSITION CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11054743-B2 Fluorene polyfunctional photoinitiator and preparation and use thereof, and photosensitive resin composition containing fluorene photoinitiator and use thereof RARA, RARG, PFAS NPC1 4697/4885KDM4E 1443/4885LMNA 2241/4885
US-20200264508-A1 FLUORENE POLYFUNCTIONAL PHOTOINITIATOR AND PREPARATION AND USE THEREOF, AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING FLUORENE PHOTOINITIATOR AND USE THEREOF RARA, RARG, PFAS NPC1 4697/4885KDM4E 1443/4885LMNA 2241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.