⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2794651 | 0.92 | — | — | |
| SCHEMBL540663 | 0.89 | — | — | |
| Fluoride SCHEMBL29583107 | 0.89 | — | — | |
| SCHEMBL28066549 | 0.86 | OR51E2 (0.41) | — | |
| SCHEMBL3360735 | 0.83 | — | — | |
| SCHEMBL27864158 | 0.83 | CRBN (0.36) | — | |
| SCHEMBL169833 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL3405773 | 0.79 | — | — | |
| SCHEMBL11414395 | 0.79 | — | — | |
| Phosphine SCHEMBL27974343 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367099-A1 | PYRIDINONE MK2 INHIBITORS AND USES THEREOF | Xinthera, Inc. (US) | 2024-05-15 | — | — | EP | claimed |
| CN-117651698-A | Pyridone MK2 inhibitors and uses thereof | 新特拉有限公司 | 2024-03-05 | — | — | CN | claimed |
| CN-114057650-B | Method for preparing 4, 5-dihydropyridazin-3-one compounds by one-pot method | 温州大学 | 2023-03-28 | — | — | CN | claimed |
| WO-2023283338-A1 | PYRIDINONE MK2 INHIBITORS AND USES THEREOF | XINTHERA, INC. (US) | 2023-01-12 | — | — | WO | claimed |
| CN-114057650-A | Method for preparing 4, 5-dihydropyridazin-3-one compounds by one-pot method | 温州大学 | 2022-02-18 | — | — | CN | claimed |
| US-20130172323-A1 | PYRIDAZINONES AS GPR119 AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-04 | — | — | US | claimed |
| US-20090104116-A1 | COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF | JERINI AG (DE) | 2009-04-23 | — | — | US | claimed |
| EP-2049503-A1 | QUINAZOLINE AND PYRIDOPYRIMIDINE DERIVATIVES AS P38 KINASE INHIBITORS | Amgen Inc. (US) | 2009-04-22 | — | — | EP | claimed |
| EP-1979342-A1 | COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF | Jerini AG (DE) | 2008-10-15 | — | — | EP | claimed |
| US-20080032973-A1 | 2-Quinazolinone compounds and methods of use | AMGEN INC. (US) | 2008-02-07 | — | — | US | claimed |
| US-20050239808-A1 | Active substances for the treatment, diagnosis and prophylaxis of diseases in which abnormal protein structures occur | TRANSMIT GESELLSCHAFT FUR TECHNOLOGIETRANSFER MBH (DE) | 2005-10-27 | — | — | US | claimed |
| WO-2005070460-A2 | COMBINATION THERAPY WITH 5-HT1A AND 5-HT1B RECEPTOR ANTAGONISTS | RECORDATI IRELAND LIMITED (IE) | 2005-08-04 | — | — | WO | claimed |
| EP-1503990-A1 | ACTIVE SUBSTANCES FOR THE TREATMENT, DIAGNOSIS AND PROPHYLAXIS OF DISEASES IN WHICH ABNORMAL PROTEIN STRUCTURES OCCUR | Transmit Gesellschaft für Technologietransfer mbH (DE) | 2005-02-09 | — | — | EP | claimed |
| WO-2003095429-A1 | ACTIVE SUBSTANCES FOR THE TREATMENT, DIAGNOSIS AND PROPHYLAXIS OF DISEASES IN WHICH ABNORMAL PROTEIN STRUCTURES OCCUR | TransMIT Gesellschaft für Technologietransfer mbH (DE) | 2003-11-20 | — | — | WO | claimed |
| EP-0468924-A2 | New herbicides | CIBA-GEIGY AG (CH) | 1992-01-29 | — | — | EP | claimed |
| EP-0193013-B1 | BENZIMIDAZOLYL-PYRIDAZINONES | MERCK PATENT GmbH (DE) | 1989-04-19 | — | — | EP | claimed |
| EP-0272914-A2 | 6-Benzoxazinyl- and 6-benzothiazinyl-2,3,4,5-tetrahydropyridazin-3-ones | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-06-29 | — | — | EP | claimed |
| EP-0193013-A2 | Benzimidazolyl-pyridazinones | MERCK PATENT GmbH (DE) | 1986-09-03 | — | — | EP | claimed |
| EP-0129791-A2 | Tetrahydropyridazinone derivatives, process for their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1985-01-02 | — | — | EP | claimed |
| EP-0010156-A1 | 6-Arylpyridazine-3-ones, pharmaceutical compositions containing them and process for their preparation | MERCK PATENT GmbH (DE) | 1980-04-30 | — | — | EP | claimed |