Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.34 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175406 | 0.86 | — | — | |
| SCHEMBL2794651 | 0.79 | — | — | |
| 2-Pyrrolidone SCHEMBL27762483 | 0.77 | OR51E2 (0.71) | OR51E2CRBNFKBP5 | |
| SCHEMBL540663 | 0.77 | — | — | |
| SCHEMBL27864158 | 0.77 | CRBN (0.36) | OR51E2CRBNFKBP5 | |
| Fluoride SCHEMBL29583107 | 0.77 | — | — | |
| SCHEMBL28282350 | 0.75 | OR51E2 (0.31) | OR51E2 | |
| Piperidine SCHEMBL5712527 | 0.73 | ALDH1A1 (0.43) | OR51E2CRBNFKBP5 | |
| SCHEMBL279774 | 0.72 | — | — | |
| SCHEMBL3360735 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220635-B | The dihydro diaza * and carbazole ketone at the condensed Fourth Ring or five rings as PARP inhibitor | 百济神州有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-106220635-A | As the Fourth Ring condensed of PARP inhibitor or the dihydro diaza * at five rings carbazole ketone | 百济神州有限公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-103703004-B | Fused tetracyclic or pentacyclic dihydrodiaza-carbazolones as PARP inhibitors | 百济神州有限公司 | 2016-06-29 | — | — | CN | disclosed |