Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18979059 | 0.88 | SLC22A12 (0.56) | SLC22A12KCNA5KDM4EL3MBTL1 | |
| SCHEMBL17540595 | 0.88 | SLC22A12 (0.58) | SLC22A12 | |
| SCHEMBL19240220 | 0.84 | SLC22A12 (0.39) | SLC22A12KDM4EL3MBTL1 | |
| SCHEMBL18979146 | 0.82 | SLC22A12 (0.37) | SLC22A12BACE1KCNA5P2RX7PORCN | |
| SCHEMBL18979062 | 0.79 | SLC22A12 (0.61) | SLC22A12 | |
| SCHEMBL19240224 | 0.79 | SLC22A12 (0.59) | SLC22A12 | |
| SCHEMBL22938888 | 0.78 | SLC22A12 (0.53) | SLC22A12 | |
| SCHEMBL18978870 | 0.77 | SLC22A12 (0.59) | SLC22A12LATS1 | |
| SCHEMBL18978872 | 0.76 | SLC22A12 (0.46) | SLC22A12GAAKMT2AKDM4ELATS1 | |
| Darbinurad SCHEMBL17540573 | 0.76 | SLC22A12 (0.72) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022736-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | InventisBio Co., Ltd. (CN) | 2018-01-25 | — | — | US | disclosed |
| US-20180022736-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | InventisBio Co., Ltd. (CN) | 2018-01-25 | — | — | US | disclosed |
| US-9856239-B1 | Carboxylic acid compound, method for preparation thereof, and use thereof | INVENTISBIO SHANGHAI LTD. (CN) | 2018-01-02 | — | — | US | disclosed |
| US-9809580-B2 | Carboxylic acid compound, method for preparation thereof, and use thereof | INVENTISBIO SHANGHAI LTD. (CN) | 2017-11-07 | — | — | US | disclosed |
| US-9809580-B2 | Carboxylic acid compound, method for preparation thereof, and use thereof | INVENTISBIO SHANGHAI LTD. (CN) | 2017-11-07 | — | — | US | disclosed |
| US-20170233376-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | InventisBio Co., Ltd. (CN) | 2017-08-17 | — | — | US | disclosed |
| US-20170233376-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | InventisBio Co., Ltd. (CN) | 2017-08-17 | — | — | US | disclosed |
| EP-3181557-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | Shanghai Shaletech Technology Co., Ltd. (CN) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016023460-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | 上海页岩科技有限公司 | 2016-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233376-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | CA7, CYP2C9, CA9 | SLC22A12 251/4885BACE1 2145/4885GAA 253/4885 |
| US-20180022736-A1 | CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF | CA7, CYP2C9, CA9 | SLC22A12 251/4885BACE1 2145/4885GAA 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.