Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17577764 | 0.84 | TDP1 (0.40) | TDP1ALDH1A1FFAR3 | |
| SCHEMBL9463777 | 0.84 | CYP2C9 (0.46) | TDP1ALDH1A1CYP2C9TSHRFFAR3 | |
| SCHEMBL12572606 | 0.81 | LMNA (0.36) | TSHRFFAR3PDE4A | |
| SCHEMBL17574431 | 0.81 | LMNA (0.36) | TSHRFFAR3PDE4A | |
| SCHEMBL13997319 | 0.81 | LMNA (0.36) | TSHRFFAR3PDE4A | |
| SCHEMBL8507977 | 0.80 | TSHR (0.56) | TDP1ALDH1A1CYP2C9TSHRFFAR3 | |
| SCHEMBL9965104 | 0.80 | TSHR (0.56) | TDP1ALDH1A1CYP2C9TSHRFFAR3 | |
| SCHEMBL17931823 | 0.80 | CYP2C9 (0.56) | CYP2C9TSHRPDE4A | |
| SCHEMBL28137936 | 0.80 | TSHR (0.34) | TDP1ALDH1A1CYP2C9TSHRFFAR3 | |
| SCHEMBL16620971 | 0.80 | TSHR (0.34) | TDP1ALDH1A1CYP2C9TSHRFFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016025643-A1 | BRUSH-POLY(GLYCOAMIDOAMINE)-LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-02-18 | — | — | WO | disclosed |