Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15716592 | 0.89 | SYK (0.55) | SYKMAPTIDO1CCR6PAX8 | |
| SCHEMBL25346745 | 0.87 | CCR6 (0.52) | SYKMAPTIDO1CCR6PAX8 | |
| SCHEMBL25970217 | 0.87 | SYK (0.53) | SYKMAPTIDO1CCR6PAX8 | |
| SCHEMBL1543294 | 0.86 | SYK (0.48) | SYKMAPTIDO1CCR6PAX8 | |
| SCHEMBL18241722 | 0.86 | SYK (0.53) | SYKMAPTKLK7KLK5CTSS | |
| SCHEMBL12093506 | 0.86 | SYK (0.49) | SYKMAPTIDO1CCR6PAX8 | |
| SCHEMBL18251799 | 0.85 | SYK (0.49) | SYKMAPTIDO1CCR6PAX8 | |
| SCHEMBL8089817 | 0.85 | SYK (0.48) | SYKMAPTIDO1CCR6PAX8 | |
| SCHEMBL7419081 | 0.85 | SYK (0.48) | SYKMAPTIDO1CCR6PAX8 | |
| SCHEMBL2685379 | 0.84 | SYK (0.50) | SYKMAPTIDO1CCR6PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020404-A1 | PROCESS FOR THE RESOLUTION OF (R,S)-DIAZEPANE AND DIAZEPANONE DERIVATIVES | SANDOZ AG (CH) | 2016-02-11 | — | — | WO | disclosed |