SCHEMBL17545772

SCHEMBL17545772

COc1cc(N=Nc2ccc(S(=O)(=O)O)cc2)c(C)cc1N=Nc1cc(OC)c(N=Nc2c(S(=O)(=O)O)cc3cc(Nc4ccccc4)ccc3c2O)cc1OC

nearest known ligand 0.80

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 10/20 0.80
CD40 P25942 1/20 0.55
CD40LG P29965 1/20 0.55
PRMT1 Q99873 2/20 0.51
PRMT3 O60678 1/20 0.51
EP300 Q09472 1/20 0.51
PRMT6 Q96LA8 1/20 0.51
PHLPP2 Q6ZVD8 2/20 0.50
CARM1 Q86X55 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HIF1A Q16665 1/20 0.47
PTPN1 P18031 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18359582 1.00 ENPP2 (0.80) ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL29740729 1.00 ENPP2 (0.80) ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL19234942 1.00 ENPP2 (0.80) ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL14422688 1.00 ENPP2 (0.80) ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL14422684 1.00 ENPP2 (0.80) ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL13556981 1.00 ENPP2 (0.80) ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL16417275 1.00 ENPP2 (0.80) ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL29383037 1.00 ENPP2 (0.80) ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL13287624 1.00 ENPP2 (0.80) ENPP2CD40CD40LGPRMT1PRMT3
SCHEMBL19958208 0.97 ENPP2 (0.78) ENPP2CD40CD40LGPRMT1PRMT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10209418-B2 Achromatic polarization element, and polarization plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-02-19 US disclosed
US-20170153361-A1 Achromatic Polarizing Plate With High-Transmissivity And High-Degree Of Polarization NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-06-01 US disclosed
US-20160041322-A1 Achromatic Polarization Element, And Polarization Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-02-11 US disclosed