SCHEMBL17545808

SCHEMBL17545808

O=S(=O)(O)c1ccc(N=Nc2ccc(N=Nc3ccc(N=Nc4c(S(=O)(=O)O)cc5cc(Nc6ccccc6)ccc5c4O)cc3)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 9/20 0.69
CD40 P25942 1/20 0.64
CD40LG P29965 1/20 0.64
PRMT3 O60678 1/20 0.63
EP300 Q09472 1/20 0.63
PRMT6 Q96LA8 1/20 0.63
PRMT1 Q99873 1/20 0.63
PHLPP2 Q6ZVD8 2/20 0.60
SNCA P37840 1/20 0.53
NSD2 O96028 1/20 0.53
DUSP3 P51452 1/20 0.53
PTPN5 P54829 1/20 0.53
CASP7 P55210 1/20 0.53
CASP6 P55212 1/20 0.53
PTPN11 Q06124 1/20 0.53
MEN1 O00255 1/20 0.51
THRB P10828 1/20 0.51
KMT2A Q03164 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
ALDH1A1 P00352 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13350540 1.00 ENPP2 (0.69) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL12757456 1.00 ENPP2 (0.69) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL17540343 0.94 PRMT1 (0.69) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL17515769 0.94 PRMT1 (0.69) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL29538227 0.93 ENPP2 (0.71) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL20735469 0.93 ENPP2 (0.61) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL20735270 0.92 CD40 (0.64) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL20735312 0.92 CD40 (0.64) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL19234940 0.92 CD40 (0.67) ENPP2CD40CD40LGPRMT3EP300
SCHEMBL17545761 0.92 ENPP2 (0.69) ENPP2CD40CD40LGPRMT3EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10209418-B2 Achromatic polarization element, and polarization plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-02-19 US disclosed
US-20170153361-A1 Achromatic Polarizing Plate With High-Transmissivity And High-Degree Of Polarization NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-06-01 US disclosed
US-20160041322-A1 Achromatic Polarization Element, And Polarization Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-02-11 US disclosed