Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | PPARD | Q03181 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061319 | 0.80 | MAPT (0.41) | KMT2AMAPTMEN1ATML3MBTL1 | |
| SCHEMBL11869885 | 0.80 | MEN1 (0.54) | KMT2AMAPTMEN1ATML3MBTL1 | |
| SCHEMBL8061623 | 0.80 | KMT2A (0.47) | KMT2AMAPTMEN1FAAHHAO1 | |
| SCHEMBL9514231 | 0.80 | KMT2A (0.52) | KMT2AMAPTMEN1FAAHHAO1 | |
| SCHEMBL8849887 | 0.75 | CYP4F2 (0.46) | KMT2AMAPTMEN1ATML3MBTL1 | |
| SCHEMBL17617207 | 0.75 | CYP4F2 (0.46) | KMT2AMAPTMEN1ATML3MBTL1 | |
| SCHEMBL18380792 | 0.75 | MEN1 (0.57) | KMT2AMAPTMEN1ATML3MBTL1 | |
| SCHEMBL21214454 | 0.75 | MEN1 (0.57) | KMT2AMAPTMEN1ATML3MBTL1 | |
| SCHEMBL18909478 | 0.75 | MEN1 (0.57) | KMT2AMAPTMEN1ATML3MBTL1 | |
| SCHEMBL7108518 | 0.75 | KMT2A (0.43) | KMT2AMAPTMEN1FAAHHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9272260-B2 | Methods of synthesis and purification by use of a solid support | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2016-03-01 | — | — | US | disclosed |