Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 8/20 | 0.42 |
| ▸ | CES1 | P23141 | 8/20 | 0.42 |
| ▸ | CES2 | O00748 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514231 | 0.81 | KMT2A (0.52) | KMT2AMAPTFAAHCES1CES2 | |
| SCHEMBL8061623 | 0.81 | KMT2A (0.47) | KMT2AMAPTFAAHCES1CES2 | |
| SCHEMBL22681751 | 0.78 | FAAH (0.59) | KMT2AFAAHCES1CES2MEN1 | |
| SCHEMBL9514227 | 0.77 | GPR84 (0.52) | KMT2AFAAHCES1CES2MEN1 | |
| SCHEMBL19226597 | 0.77 | NAAA (0.44) | KMT2AFAAHCES1CES2MEN1 | |
| SCHEMBL31511750 | 0.76 | FAAH (0.58) | KMT2AFAAHCES1CES2MEN1 | |
| SCHEMBL17546722 | 0.75 | KMT2A (0.42) | KMT2AMAPTFAAHCES1CES2 | |
| SCHEMBL9177158 | 0.74 | KMT2A (0.52) | KMT2AMAPTFAAHCES1CES2 | |
| SCHEMBL8897068 | 0.74 | KMT2A (0.52) | KMT2AMAPTFAAHCES1CES2 | |
| SCHEMBL8096569 | 0.74 | KMT2A (0.52) | KMT2AMAPTFAAHCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001944-B1 | PYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-10-01 | — | — | EP | disclosed |