SCHEMBL17548680

SCHEMBL17548680

COc1ccc(-c2cc(-c3ccccc3)cc(-c3ccc4c5ccc(-c6cc(OC)cc(-c7cccc(-c8ccccc8)c7)c6)cc5c5ccccc5c4c3)c2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 3/20 0.72
ABCB1 P08183 3/20 0.72
BCR P11274 3/20 0.72
CYP1A2 P05177 2/20 0.59
CYP3A4 P08684 2/20 0.59
CYP2C9 P11712 2/20 0.59
CYP2B6 P20813 2/20 0.59
CYP1A1 P04798 1/20 0.59
CYP2E1 P05181 1/20 0.59
CYP2C8 P10632 1/20 0.59
CYP2D6 P10635 1/20 0.59
CYP2A6 P11509 1/20 0.59
CYP4B1 P13584 1/20 0.59
CYP3A5 P20815 1/20 0.59
CYP2A7 P20853 1/20 0.59
CYP3A7 P24462 1/20 0.59
CYP2F1 P24903 1/20 0.59
CYP2C18 P33260 1/20 0.59
CYP2C19 P33261 1/20 0.59
CYP2J2 P51589 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19910963 0.88 ABL1 (0.55) ABL1ABCB1BCRCYP3A4ACACA
SCHEMBL1615369 0.86 CYP1A2 (0.57) ABL1ABCB1BCRCYP1A2CYP3A4
SCHEMBL17552364 0.86 ABL1 (0.53) ABL1ABCB1BCRCYP1A2CYP3A4
SCHEMBL1615035 0.84 CYP1A2 (0.53) ABL1ABCB1BCRCYP1A2CYP3A4
SCHEMBL2809119 0.84 CYP1A2 (0.53) ABL1ABCB1BCRCYP1A2CYP3A4
SCHEMBL27649742 0.84 ABL1 (0.77) ABL1ABCB1BCRCYP1A2CYP3A4
SCHEMBL26498789 0.84 CYP1A1 (0.83) ABL1ABCB1BCRCYP1A2CYP3A4
SCHEMBL26498734 0.84 CYP1A1 (0.83) ABL1ABCB1BCRCYP1A2CYP3A4
SCHEMBL26498639 0.84 CYP1A1 (0.83) ABL1ABCB1BCRCYP1A2CYP3A4
SCHEMBL24712638 0.82 MEN1 (0.46) ABL1ABCB1BCRCYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9944846-B2 Compositions for electronic applications E I DU PONT DE NEMOURS AND COMPANY (US) 2018-04-17 US disclosed
US-20160060512-A1 COMPOSITIONS FOR ELECTRONIC APPLICATIONS LG CHEM, LTD. (KR) 2016-03-03 US disclosed
WO-2016033167-A1 COMPOSITIONS FOR ELECTRONIC APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2016-03-03 WO disclosed