SCHEMBL2809119

SCHEMBL2809119

COc1cccc(-c2ccc3c4ccccc4c4ccc(-c5cccc(OC)c5)cc4c3c2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.53
CYP3A4 P08684 5/20 0.53
CYP2C9 P11712 4/20 0.53
CYP2C19 P33261 4/20 0.53
CYP2D6 P10635 3/20 0.53
CYP2B6 P20813 2/20 0.53
CYP1A1 P04798 1/20 0.53
CYP2E1 P05181 1/20 0.53
CYP2C8 P10632 1/20 0.53
CYP2A6 P11509 1/20 0.53
CYP4B1 P13584 1/20 0.53
CYP3A5 P20815 1/20 0.53
CYP2A7 P20853 1/20 0.53
CYP3A7 P24462 1/20 0.53
CYP2F1 P24903 1/20 0.53
CYP2C18 P33260 1/20 0.53
CYP2J2 P51589 1/20 0.53
CYP4F2 P78329 1/20 0.53
CYP4F8 P98187 1/20 0.53
CYP4A11 Q02928 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1615035 1.00 CYP1A2 (0.53) CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6
SCHEMBL1615369 0.98 CYP1A2 (0.57) CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6
SCHEMBL15996334 0.92 ACHE (0.56) CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6
SCHEMBL17548680 0.84 ABL1 (0.72) CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6
SCHEMBL19910963 0.84 ABL1 (0.55) CYP3A4MAP4K4ABL1ABCB1BCR
SCHEMBL13247865 0.84 ABL1 (0.64) CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6
SCHEMBL1180343 0.83 ABL1 (0.69) CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6
SCHEMBL196765 0.83 CYP3A4 (0.73) CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6
SCHEMBL29489425 0.83 CYP3A4 (0.73) CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6
SCHEMBL19910965 0.83 HSD17B1 (0.61) CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3159333-B1 BENZO-FUSED THIOPHENE OR FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORP (US) 2020-04-22 EP disclosed
US-10374171-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-06 US disclosed
US-10374171-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-06 US disclosed
US-20180261778-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-09-13 US disclosed
US-9997727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-04-27 US disclosed
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-04-27 US disclosed
EP-3159333-A2 BENZO-FUSED THIOPHENE OR FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP Universal Display Corporation (US) 2017-04-26 EP disclosed
US-9577200-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-02-21 US disclosed
US-8822708-B2 Benzo-fused thiophene / triphenylene hybrid materials UNIVERSAL DISPLAY CORPORATION (US) 2014-09-02 US disclosed
US-8822708-B2 Benzo-fused thiophene / triphenylene hybrid materials UNIVERSAL DISPLAY CORPORATION (US) 2014-09-02 US disclosed
US-20130175510-A1 BENZO-FUSED THIOPHENE / TRIPHENYLENE HYBRID MATERIALS UNIVERSAL DISPLAY CORPORTION (US) 2013-07-11 US disclosed
US-8367850-B2 Benzo-fused thiophene or benzo-fused furan compounds comprising a triphenylene group UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 US disclosed
US-8367850-B2 Benzo-fused thiophene or benzo-fused furan compounds comprising a triphenylene group UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 US disclosed
US-8367850-B2 Benzo-fused thiophene or benzo-fused furan compounds comprising a triphenylene group UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 US disclosed
WO-2009021126-A9 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-09-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180261778-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TPR, EED, TEAD2 CYP1A2 2276/4885CYP3A4 913/4885CYP2C9 1129/4885
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group TFEB, BRD4, TEC CYP1A2 1616/4885CYP3A4 389/4885CYP2C9 568/4885
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TPR, EED, TEC CYP1A2 2381/4885CYP3A4 1047/4885CYP2C9 1154/4885
US-10374171-B2 Organic electroluminescent materials and devices TPR, EED, TEAD2 CYP1A2 2276/4885CYP3A4 913/4885CYP2C9 1129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.