Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1785955 | 0.92 | ALDH1A1 (0.69) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL10332467 | 0.90 | MAPT (0.56) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL28686071 | 0.87 | ALDH1A1 (0.68) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL14639874 | 0.86 | ALDH1A1 (0.53) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL7899605 | 0.86 | ALDH1A1 (0.61) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL17001644 | 0.86 | ALDH1A1 (0.61) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL14956200 | 0.85 | ALDH1A1 (0.65) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL561495 | 0.85 | ALDH1A1 (0.65) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| Benzoic Acid 2-Methylpropyl Ester SCHEMBL20530394 | 0.85 | TSHR (0.69) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL571219 | 0.85 | ALDH1A1 (0.69) | ALDH1A1ADRB2ADRB1ADRB3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441475-A1 | Reduced temperature sterilization of stents | Abbott Cardiovascular Systems Inc. (US) | 2012-04-18 | — | — | EP | disclosed |
| EP-1533305-A1 | A process for the preparation of valsartan and intermediates thereof | Dipharma S.p.A. (IT) | 2005-05-25 | — | — | EP | disclosed |