Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12593832 | 0.88 | AAK1 (0.48) | AAK1MTNR1BALDH1A1KMT2AMTNR1A | |
| SCHEMBL21580667 | 0.87 | AAK1 (0.48) | AAK1 | |
| SCHEMBL31089796 | 0.87 | AAK1 (0.48) | AAK1 | |
| SCHEMBL1978552 | 0.86 | XIAP (0.55) | AAK1MTNR1BKMT2AMTNR1ALTA4H | |
| SCHEMBL18590762 | 0.86 | AAK1 (0.42) | AAK1MTNR1BLTA4H | |
| SCHEMBL1983127 | 0.86 | AAK1 (0.48) | AAK1ALDH1A1KMT2ALTA4H | |
| SCHEMBL20906310 | 0.86 | AAK1 (0.48) | AAK1ALDH1A1KMT2ALTA4H | |
| SCHEMBL1978742 | 0.86 | AAK1 (0.48) | AAK1ALDH1A1KMT2ALTA4H | |
| Hydrochloric Acid SCHEMBL21980915 | 0.85 | AAK1 (0.47) | AAK1ALDH1A1KMT2ALTA4H | |
| Hydrochloric Acid SCHEMBL13720612 | 0.85 | AAK1 (0.47) | AAK1ALDH1A1KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160058737-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | AUTIFONY THERAPEUTICS LIMITED (GB) | 2016-03-03 | — | — | US | disclosed |
| US-20160058737-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | AUTIFONY THERAPEUTICS LIMITED (GB) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160058737-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | KCND3, KCNK3, KCNA3 | AAK1 1159/4885MTNR1B 1903/4885ALDH1A1 848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.