Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21580667 | 1.00 | AAK1 (0.48) | AAK1GRM5 | |
| SCHEMBL17549697 | 0.87 | AAK1 (0.48) | AAK1 | |
| SCHEMBL1978742 | 0.84 | AAK1 (0.48) | AAK1 | |
| SCHEMBL20906310 | 0.84 | AAK1 (0.48) | AAK1 | |
| SCHEMBL1983127 | 0.84 | AAK1 (0.48) | AAK1 | |
| Hydrochloric Acid SCHEMBL21980915 | 0.84 | AAK1 (0.47) | AAK1 | |
| Hydrochloric Acid SCHEMBL13720612 | 0.84 | AAK1 (0.47) | AAK1 | |
| SCHEMBL21581606 | 0.83 | DYRK1A (0.48) | GRM5 | |
| SCHEMBL21581662 | 0.81 | HDAC4 (0.41) | AAK1GRM5 | |
| SCHEMBL31089865 | 0.81 | HDAC4 (0.41) | AAK1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12090146-B2 | Substituted-pyridinyl compounds and uses thereof | BIONOMICS LIMITED (AU) | 2024-09-17 | — | — | US | disclosed |
| EP-3853216-B1 | 3-[2-(PHENOXY)-4-PYRIDYL]-IMIDAZOLIDINE-2,4-DIONE DERIVATIVES FOR THE TREATMENT OF COGNITIVE DYSFUNCTION AND CNS DISORDERS | BIONOMICS LTD (AU) | 2024-09-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12090146-B2 | Substituted-pyridinyl compounds and uses thereof | GABRE, GAP43, GRIN2A | AAK1 1588/4885GRM5 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.