Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 18/20 | 0.64 |
| ▸ | FPR1 | P21462 | 1/20 | 0.64 |
| ▸ | GPR183 | P32249 | 1/20 | 0.64 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.64 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16238104 | 0.96 | GNRHR (0.63) | GNRHRFPR1GPR183GPR119CACNA1F | |
| SCHEMBL16254097 | 0.92 | GNRHR (0.65) | GNRHRFPR1GPR183GPR119 | |
| SCHEMBL17549861 | 0.90 | GNRHR (0.63) | GNRHRFPR1GPR183GPR119CACNA1F | |
| SCHEMBL16237594 | 0.90 | GNRHR (0.63) | GNRHRFPR1GPR183GPR119CACNA1F | |
| SCHEMBL17552170 | 0.87 | GNRHR (0.70) | GNRHRFPR1GPR183GPR119 | |
| SCHEMBL16238034 | 0.86 | GNRHR (0.58) | GNRHRFPR1GPR183GPR119CACNA1F | |
| SCHEMBL16254082 | 0.86 | GNRHR (0.61) | GNRHRFPR1GPR183GPR119CACNA1F | |
| SCHEMBL17552135 | 0.85 | GNRHR (0.68) | GNRHRFPR1GPR183GPR119 | |
| SCHEMBL16254098 | 0.84 | GNRHR (0.70) | GNRHRFPR1GPR183GPR119 | |
| SCHEMBL16238189 | 0.83 | GNRHR (0.69) | GNRHRFPR1GPR183GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160058895-A1 | RADIOLABELED GNRH ANTAGONISTS AS PET IMAGING AGENTS | OSLO UNIVERSITETSSYKEHUS HF (NO) | 2016-03-03 | — | — | US | disclosed |
| US-20160058895-A1 | RADIOLABELED GNRH ANTAGONISTS AS PET IMAGING AGENTS | OSLO UNIVERSITETSSYKEHUS HF (NO) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160058895-A1 | RADIOLABELED GNRH ANTAGONISTS AS PET IMAGING AGENTS | GNRHR, FSHR, GHRHR | GNRHR 1/4885FPR1 759/4885GPR183 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.