Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5671480 | 0.95 | KDM4E (0.35) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL16323633 | 0.87 | MEN1 (0.36) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL203915 | 0.84 | CES2 (0.43) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| Hydrochloric Acid SCHEMBL11033629 | 0.81 | CES2 (0.42) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL336420 | 0.81 | CES2 (0.42) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL16756190 | 0.81 | CES2 (0.42) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL2150002 | 0.81 | CES2 (0.42) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| Ammonia Solution, Strong SCHEMBL20291864 | 0.81 | CES2 (0.42) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL28389339 | 0.81 | CES2 (0.42) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL7776700 | 0.81 | CES2 (0.42) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016030329-A1 | METHOD FOR THE PRODUCTION OF 18F-LABELED ACTIVE ESTERS AND THEIR APPLICATION EXEMPLIFIED BY THE PREPARATION OF A PSMA-SPECIFIC PET-TRACER | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-03-03 | — | — | WO | disclosed |