Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1751213 | 0.97 | — | — | |
| SCHEMBL5223845 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL17550738 | 0.94 | — | — | |
| Bromide SCHEMBL28631224 | 0.92 | TSHR (0.50) | — | |
| Bromide SCHEMBL25406243 | 0.90 | TSHR (0.55) | — | |
| SCHEMBL2231055 | 0.89 | — | — | |
| SCHEMBL334434 | 0.86 | TSHR (0.58) | — | |
| SCHEMBL18807792 | 0.86 | TSHR (0.58) | — | |
| SCHEMBL7285272 | 0.86 | TSHR (0.58) | — | |
| SCHEMBL7294715 | 0.86 | TSHR (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278907-B2 | Use of 4-[ethyl(dimethyl)ammonio]butanoate in the treatment of cardiovascular disease | JSC GRINDEKS (LV) | 2016-03-08 | — | — | US | claimed |
| CN-113227040-A | Nanoparticles, nuclear magnetic resonance imaging contrast agent containing nanoparticles and zwitterionic ligand compound | 安斯泰来制药株式会社 | 2021-08-06 | — | — | CN | disclosed |
| CN-107082747-B | Compounds for targeted drug delivery and enhancing siRNA activity | 日东电工株式会社 | 2020-11-20 | — | — | CN | disclosed |
| CN-107043334-B | Compounds for targeted drug delivery and enhancing siRNA activity | 日东电工株式会社 | 2020-06-16 | — | — | CN | disclosed |
| CN-107082747-A | Conveyed for targeted drug and strengthen the compound of siRNA activity | 日东电工株式会社 | 2017-08-22 | — | — | CN | disclosed |
| CN-107043334-A | Conveyed for targeted drug and strengthen the compound of siRNA activity | 日东电工株式会社 | 2017-08-15 | — | — | CN | disclosed |
| CN-103857654-B | Compounds for targeted drug delivery and enhancing siRNA activity | 日东电工株式会社 | 2017-03-15 | — | — | CN | disclosed |