Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282265 | 0.97 | TSHR (0.58) | TSHRALDH1A1DNM1FAAHTRPV1 | |
| SCHEMBL7285272 | 0.97 | TSHR (0.58) | TSHRALDH1A1DNM1FAAHTRPV1 | |
| SCHEMBL7284860 | 0.97 | TSHR (0.58) | TSHRALDH1A1DNM1FAAHTRPV1 | |
| Bromide SCHEMBL28631224 | 0.97 | TSHR (0.50) | TSHRALDH1A1DNM1FAAHTRPV1 | |
| SCHEMBL18807792 | 0.97 | TSHR (0.58) | TSHRALDH1A1DNM1FAAHTRPV1 | |
| SCHEMBL7291004 | 0.97 | TSHR (0.58) | TSHRALDH1A1DNM1FAAHTRPV1 | |
| SCHEMBL951795 | 0.97 | TSHR (0.58) | TSHRALDH1A1DNM1FAAHTRPV1 | |
| SCHEMBL334434 | 0.97 | TSHR (0.58) | TSHRALDH1A1DNM1FAAHTRPV1 | |
| SCHEMBL7294715 | 0.97 | TSHR (0.58) | TSHRALDH1A1DNM1FAAHTRPV1 | |
| SCHEMBL5226044 | 0.95 | TSHR (0.55) | TSHRALDH1A1DNM1FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482844-A1 | SILOXANE DERIVATIVES OF AMINO ACIDS HAVING SURFACE-ACTIVE PROPERTIES | AdvanSix Resins & Chemicals LLC (US) | 2025-01-01 | — | — | EP | claimed |
| WO-2023163986-A1 | SILOXANE DERIVATIVES OF AMINO ACIDS HAVING SURFACE-ACTIVE PROPERTIES | ADVANSIX RESINS & CHEMICALS LLC (US) | 2023-08-31 | — | — | WO | claimed |
| US-20230265112-A1 | SILOXANE DERIVATIVES OF AMINO ACIDS HAVING SURFACE-ACTIVE PROPERTIES | ADVANSIX RESINS & CHEMICALS LLC (US) | 2023-08-24 | — | — | US | claimed |
| WO-2025034834-A1 | SURFACTANTS FOR INKS, PAINTS, AND ADHESIVES | ADVANSIX RESINS & CHEMICALS LLC (US) | 2025-02-13 | — | — | WO | disclosed |
| WO-2025034846-A1 | SURFACTANTS FOR OIL AND GAS PRODUCTION | ADVANSIX RESINS & CHEMICALS LLC (US) | 2025-02-13 | — | — | WO | disclosed |
| WO-2025034841-A1 | SURFACTANTS FOR ELECTRONICS | ADVANSIX RESINS & CHEMICALS LLC (US) | 2025-02-13 | — | — | WO | disclosed |
| WO-2025034831-A1 | SURFACTANTS FOR CLEANING PRODUCTS | ADVANSIX RESINS & CHEMICALS LLC (US) | 2025-02-13 | — | — | WO | disclosed |
| WO-2025034837-A1 | SURFACTANTS FOR USE IN HEALTHCARE PRODUCTS | ADVANSIX RESINS & CHEMICALS LLC (US) | 2025-02-13 | — | — | WO | disclosed |
| EP-4482844-A1 | SILOXANE DERIVATIVES OF AMINO ACIDS HAVING SURFACE-ACTIVE PROPERTIES | AdvanSix Resins & Chemicals LLC (US) | 2025-01-01 | — | — | EP | disclosed |
| WO-2023163986-A1 | SILOXANE DERIVATIVES OF AMINO ACIDS HAVING SURFACE-ACTIVE PROPERTIES | ADVANSIX RESINS & CHEMICALS LLC (US) | 2023-08-31 | — | — | WO | disclosed |
| US-20230265112-A1 | SILOXANE DERIVATIVES OF AMINO ACIDS HAVING SURFACE-ACTIVE PROPERTIES | ADVANSIX RESINS & CHEMICALS LLC (US) | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265112-A1 | SILOXANE DERIVATIVES OF AMINO ACIDS HAVING SURFACE-ACTIVE PROPERTIES | BCAT1, PCMT1, LTN1 | SIGMAR1 479/4885TSHR 4450/4885ALDH1A1 4398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.