SCHEMBL17550796

SCHEMBL17550796

CCCCCSc1nnc(SC)s1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
APEX1 P27695 1/20 0.40
USP2 O75604 1/20 0.38
SMN1; SMN2 Q16637 6/20 0.38
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
CYP1A2 P05177 1/20 0.37
HTT P42858 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 3/20 0.36
MAPT P10636 3/20 0.36
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 2/20 0.35
GAA P10253 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10797452 0.92 ALDH1A1 (0.72) ALDH1A1APEX1USP2SMN1; SMN2CYP2C9
SCHEMBL11423947 0.90 ALDH1A1 (0.76) ALDH1A1APEX1USP2SMN1; SMN2CYP2C9
SCHEMBL28887982 0.90 ALDH1A1 (0.76) ALDH1A1APEX1USP2SMN1; SMN2CYP2C9
SCHEMBL7797173 0.90 ALDH1A1 (0.76) ALDH1A1APEX1USP2SMN1; SMN2CYP2C9
SCHEMBL2772386 0.90 ALDH1A1 (0.76) ALDH1A1APEX1USP2SMN1; SMN2CYP2C9
SCHEMBL14582782 0.88 ALDH1A1 (0.47) ALDH1A1APEX1USP2SMN1; SMN2HTT
SCHEMBL10797194 0.86 ALDH1A1 (0.63) ALDH1A1APEX1USP2SMN1; SMN2HTT
SCHEMBL9777349 0.81 ALDH1A1 (0.65) ALDH1A1APEX1USP2SMN1; SMN2HTT
SCHEMBL8523619 0.81 ALDH1A1 (0.64) ALDH1A1CYP2C9CYP2C19CYP1A2L3MBTL1
SCHEMBL6361818 0.80 ALDH1A1 (0.58) ALDH1A1APEX1USP2SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160064674-A1 ORGANIC SEMICONDUCTOR COMOSITION, ORGANIC THIN-FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-03-03 US disclosed