Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17551907 | 0.83 | SLC1A2 (0.41) | SLC1A2SLC1A1 | |
| SCHEMBL19286583 | 0.78 | SLC1A2 (0.32) | SLC1A2SLC1A1 | |
| SCHEMBL4198280 | 0.78 | — | — | |
| SCHEMBL15827323 | 0.77 | SLC1A2 (0.34) | SLC1A2SLC1A1 | |
| SCHEMBL16205272 | 0.77 | SLC1A2 (0.34) | SLC1A2SLC1A1 | |
| SCHEMBL12194584 | 0.71 | SLC1A2 (0.34) | SLC1A2SLC1A1 | |
| SCHEMBL17037459 | 0.71 | SLC1A2 (0.34) | SLC1A2SLC1A1 | |
| SCHEMBL2841706 | 0.70 | EPHX1 (0.35) | SLC1A2SLC1A1 | |
| SCHEMBL10793287 | 0.70 | EPHX1 (0.35) | SLC1A2SLC1A1 | |
| SCHEMBL2844101 | 0.70 | EPHX1 (0.35) | SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745295-B2 | Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-08-29 | — | — | US | disclosed |
| US-20160060255-A1 | THIAZOLE-SUBSTITUTED AMINOHETEROARYLS AS SPLEEN TYROSINE KINASE INHIBITORS | MERCK CANADA INC. (CA) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060255-A1 | THIAZOLE-SUBSTITUTED AMINOHETEROARYLS AS SPLEEN TYROSINE KINASE INHIBITORS | SYK, TYRO3, BTK | SLC1A2 2962/4885SLC1A1 1946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.