Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14060113 | 1.00 | DGAT1 (0.70) | DGAT1 | |
| SCHEMBL14059936 | 0.93 | DGAT1 (0.81) | DGAT1 | |
| SCHEMBL14060410 | 0.88 | DGAT1 (0.81) | DGAT1 | |
| SCHEMBL17200558 | 0.84 | DGAT1 (0.84) | DGAT1 | |
| SCHEMBL14059682 | 0.84 | DGAT1 (0.81) | DGAT1 | |
| SCHEMBL14059919 | 0.83 | DGAT1 (0.83) | DGAT1 | |
| SCHEMBL14059848 | 0.82 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL17200594 | 0.82 | DGAT1 (0.85) | DGAT1 | |
| SCHEMBL14137123 | 0.82 | DGAT1 (0.85) | DGAT1 | |
| SCHEMBL14137119 | 0.82 | DGAT1 (0.85) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723332-B1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2016-03-02 | — | — | EP | disclosed |