Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 19/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14061863 | 0.89 | DGAT1 (0.77) | DGAT1 | |
| SCHEMBL14137111 | 0.89 | DGAT1 (0.77) | DGAT1 | |
| SCHEMBL17552048 | 0.85 | DGAT1 (0.65) | DGAT1 | |
| SCHEMBL14060357 | 0.79 | DGAT1 (0.73) | DGAT1 | |
| SCHEMBL14061930 | 0.79 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL14137105 | 0.79 | DGAT1 (0.69) | DGAT1 | |
| SCHEMBL17211838 | 0.77 | DGAT1 (0.77) | DGAT1 | |
| SCHEMBL17200623 | 0.76 | DGAT1 (0.76) | DGAT1 | |
| SCHEMBL14059735 | 0.76 | DGAT1 (0.76) | DGAT1 | |
| SCHEMBL14060362 | 0.76 | DGAT1 (0.72) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723332-B1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2016-03-02 | — | — | EP | disclosed |