Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QARS1 | P47897 | 1/20 | 0.38 |
| ▸ | AGL | P35573 | 2/20 | 0.31 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13892976 | 0.76 | QARS1 (0.36) | QARS1 | |
| SCHEMBL26893956 | 0.74 | — | — | |
| SCHEMBL2275662 | 0.74 | — | — | |
| SCHEMBL18410484 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL3579781 | 0.72 | — | — | |
| SCHEMBL20726333 | 0.70 | QARS1 (0.33) | QARS1 | |
| SCHEMBL20311013 | 0.69 | — | — | |
| SCHEMBL8910466 | 0.69 | — | — | |
| SCHEMBL20282958 | 0.69 | — | — | |
| SCHEMBL21325848 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896083-B1 | A METHOD FOR THE TREATMENT OF POMPE DISEASE USING 1-DEOXYNOJIRIMYCIN AND DERIVATIVES | AMICUS THERAPEUTICS INC (US) | 2016-03-02 | — | — | EP | disclosed |