SCHEMBL1755243

SCHEMBL1755243

C=[N+]([O-])c1ccccc1C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.60
TSHR P16473 4/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
ALDH1A1 P00352 7/20 0.44
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ACHE P22303 2/20 0.43
PKM P14618 1/20 0.43
TDP1 Q9NUW8 5/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
LMNA P02545 1/20 0.37
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25977774 0.77 HSD17B10 (0.50) HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT
SCHEMBL11227424 0.75 HSD17B10 (0.60) HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT
SCHEMBL29859415 0.75 HSD17B10 (1.00) HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT
SCHEMBL5700792 0.75 HSD17B10 (0.60) HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT
SCHEMBL28553719 0.75 HSD17B10 (0.60) HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT
SCHEMBL26788 0.75 HSD17B10 (1.00) HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT
SCHEMBL8044782 0.73 HSD17B10 (0.95) HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT
SCHEMBL8044778 0.73 HSD17B10 (0.95) HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT
SCHEMBL11125458 0.73 HSD17B10 (0.95) HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT
Ammonia Solution, Strong SCHEMBL9579917 0.73 HSD17B10 (0.95) HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250084070-A1 PROCESS FOR THE SYNTHESIS OF 5-((2-METHYL-1H-IMIDAZOL-1-YL)METHYL)FURAN-2-CARBALDEHYDE AND OF NITRONES FROM 5-((2-METHYL-1H-IMIDAZOL-1-YL)METHYL)FURAN-2-CARBALDEHYDE COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2025-03-13 US disclosed
EP-1569919-B1 NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS BOEHRINGER INGELHEIM INT (DE) 2012-04-18 EP disclosed
EP-2230312-A1 Probe compound for detecting and isolating enzymes and means and methods using the same Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084070-A1 PROCESS FOR THE SYNTHESIS OF 5-((2-METHYL-1H-IMIDAZOL-1-YL)METHYL)FURAN-2-CARBALDEHYDE AND OF NITRONES FROM 5-((2-METHYL-1H-IMIDAZOL-1-YL)METHYL)FURAN-2-CARBALDEHYDE MGAT1, B3GNT2, NPM1 HSD17B10 2777/4885TSHR 4756/4885SMN1; SMN2 1070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.