Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18185042 | 0.81 | TSHR (0.63) | HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11227424 | 0.75 | HSD17B10 (0.60) | HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL29859415 | 0.75 | HSD17B10 (1.00) | HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1755243 | 0.75 | HSD17B10 (0.60) | HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL26788 | 0.75 | HSD17B10 (1.00) | HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL28553719 | 0.75 | HSD17B10 (0.60) | HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8044778 | 0.73 | HSD17B10 (0.95) | HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11125458 | 0.73 | HSD17B10 (0.95) | HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8044782 | 0.73 | HSD17B10 (0.95) | HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL9579917 | 0.73 | HSD17B10 (0.95) | HSD17B10TSHRSMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |