Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 1/20 | 0.43 |
| ▸ | LIG1 | P18858 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14541663 | 0.86 | PCNA (0.43) | PCNALIG1SCN4AESR1ESR2 | |
| SCHEMBL28035205 | 0.86 | PCNA (0.43) | PCNALIG1SCN4AESR1ESR2 | |
| SCHEMBL22563604 | 0.80 | PCNA (0.46) | PCNALIG1SCN4ATHRATHRB | |
| SCHEMBL30123655 | 0.80 | PCNA (0.46) | PCNALIG1SCN4ATHRATHRB | |
| SCHEMBL1702318 | 0.80 | PCNA (0.46) | PCNALIG1SCN4ATHRATHRB | |
| Bromide SCHEMBL11693753 | 0.77 | PCNA (0.42) | PCNALIG1ESR1TAAR1SLC6A2 | |
| SCHEMBL11695160 | 0.72 | PCNA (0.50) | PCNALIG1TAAR1SLC6A2EPHX1 | |
| SCHEMBL1960568 | 0.72 | PLA2G1B (0.59) | PCNALIG1ESR1TAAR1SLC6A2 | |
| SCHEMBL16124486 | 0.72 | PCNA (0.58) | PCNALIG1THRATHRBTAAR1 | |
| SCHEMBL4968038 | 0.72 | PLA2G1B (0.59) | PCNALIG1ESR1TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937689-B1 | INTERMEDIATE AND PROCESS OF PREPARATION OF ECTEINASCIDINS SUCH AS ECTEINASCIDINS 583 AND 597 USING SUCH INTERMEDIATE | CENTRE NAT RECH SCIENT (FR) | 2012-04-18 | — | — | EP | disclosed |