Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 1/20 | 0.46 |
| ▸ | LIG1 | P18858 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.35 |
| ▸ | TUBB | P07437 | 3/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22563604 | 1.00 | PCNA (0.46) | PCNALIG1THRATHRBTDP1 | |
| SCHEMBL30123655 | 1.00 | PCNA (0.46) | PCNALIG1THRATHRBTDP1 | |
| SCHEMBL28035207 | 0.84 | CYP3A4 (0.41) | PCNALIG1MMP1CYP3A4 | |
| SCHEMBL28035206 | 0.84 | CYP3A4 (0.41) | PCNALIG1MMP1CYP3A4 | |
| SCHEMBL14493792 | 0.83 | ALOX15 (0.38) | THRATHRBTDP1MMP1CYP3A4 | |
| SCHEMBL1755280 | 0.80 | PCNA (0.43) | PCNALIG1THRATHRBSCN4A | |
| SCHEMBL28035205 | 0.80 | PCNA (0.43) | PCNALIG1THRATHRBSCN4A | |
| SCHEMBL14541663 | 0.80 | PCNA (0.43) | PCNALIG1THRATHRBSCN4A | |
| SCHEMBL1323344 | 0.79 | THRA (0.38) | THRATHRBTDP1TUBB4ATUBB | |
| SCHEMBL3291891 | 0.79 | THRB (0.58) | PCNATHRATHRBTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120647544-A | Preparation method of (S) -3-hydroxy-4-methoxy-5-methyl phenylalaninol | 浙江中科创越药业有限公司 | 2025-09-16 | — | — | CN | disclosed |
| CN-120647544-A | Preparation method of (S) -3-hydroxy-4-methoxy-5-methyl phenylalaninol | 浙江中科创越药业有限公司 | 2025-09-16 | — | — | CN | disclosed |
| US-11339179-B2 | Preparation for natural product trabectedin | CE PHARM CO., LTD. (CN) | 2022-05-24 | — | — | US | disclosed |
| US-20210163500-A1 | PREPARATION FOR NATURAL PRODUCT TRABECTEDIN | CE PHARM CO., LTD. (CN) | 2021-06-03 | — | — | US | disclosed |
| EP-3725792-A1 | PREPARATION FOR NATURAL PRODUCT TRABECTEDIN | CE Pharm Co.,Ltd (CN) | 2020-10-21 | — | — | EP | disclosed |
| EP-1937689-B1 | INTERMEDIATE AND PROCESS OF PREPARATION OF ECTEINASCIDINS SUCH AS ECTEINASCIDINS 583 AND 597 USING SUCH INTERMEDIATE | CENTRE NAT RECH SCIENT (FR) | 2012-04-18 | — | — | EP | disclosed |
| EP-1937689-B1 | INTERMEDIATE AND PROCESS OF PREPARATION OF ECTEINASCIDINS SUCH AS ECTEINASCIDINS 583 AND 597 USING SUCH INTERMEDIATE | CENTRE NAT RECH SCIENT (FR) | 2012-04-18 | — | — | EP | disclosed |
| US-8058435-B2 | Intermediate and process of preparation of ecteinascidin such as ecteinascidines-583,597 using such intermediate | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-11-15 | — | — | US | disclosed |
| US-8058435-B2 | Intermediate and process of preparation of ecteinascidin such as ecteinascidines-583,597 using such intermediate | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-11-15 | — | — | US | disclosed |
| US-20090171080-A1 | Intermediate and Process of Preparation of Ecteinascidin Such as Ecteinascidines-583,597 Using Such Intermediate | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-07-02 | — | — | US | disclosed |
| US-20090171080-A1 | Intermediate and Process of Preparation of Ecteinascidin Such as Ecteinascidines-583,597 Using Such Intermediate | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-07-02 | — | — | US | disclosed |
| EP-1937689-A2 | INTERMEDIATE AND PROCESS OF PREPARATION OF ECTEINASCIDIN SUCH AS ECTEINASCIDINES-583, 597 USING SUCH INTERMEDIATE | Centre National de la Recherche Scientifique (FR) | 2008-07-02 | — | — | EP | disclosed |
| EP-1792904-A1 | Intermediate and process of preparation of ecteinascidin using such intermediate | Centre National de la Recherche Scientifique (CNRS) (FR) | 2007-06-06 | — | — | EP | disclosed |
| EP-1792904-A1 | Intermediate and process of preparation of ecteinascidin using such intermediate | Centre National de la Recherche Scientifique (CNRS) (FR) | 2007-06-06 | — | — | EP | disclosed |
| WO-2007045686-A2 | INTERMEDIATE AND PROCESS OF PREPARATION OF ECTEINASCIDIN SUCH AS ECTEINASCIDINES-583, 597 USING SUCH INTERMEDIATE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007045686-A2 | INTERMEDIATE AND PROCESS OF PREPARATION OF ECTEINASCIDIN SUCH AS ECTEINASCIDINES-583, 597 USING SUCH INTERMEDIATE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163500-A1 | PREPARATION FOR NATURAL PRODUCT TRABECTEDIN | TH, TYR, FLT4 | PCNA 4435/4885LIG1 2591/4885THRA 2949/4885 |
| US-11339179-B2 | Preparation for natural product trabectedin | TH, TYR, FLT4 | PCNA 4435/4885LIG1 2591/4885THRA 2949/4885 |
| US-20090171080-A1 | Intermediate and Process of Preparation of Ecteinascidin Such as Ecteinascidines-583,597 Using Such Intermediate | MMP7, CCR7, AREG | PCNA 2737/4885LIG1 3530/4885THRA 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.