Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2987950 | 0.87 | BRAF (0.36) | MEN1KMT2ADHODHLMNASTIM1 | |
| SCHEMBL1936462 | 0.81 | MEN1 (0.34) | MEN1KMT2ADHODHLMNASTIM1 | |
| SCHEMBL2994049 | 0.78 | BRAF (0.35) | DHODHCNR2DGAT2CSNK1DCSNK1E | |
| SCHEMBL9911854 | 0.73 | LMNA (0.31) | MEN1KMT2ADHODHLMNADGAT2 | |
| SCHEMBL2984759 | 0.73 | CYP2C8 (0.40) | CNR2DGAT2AKT1 | |
| SCHEMBL12330144 | 0.72 | PPARG (0.39) | DGAT2CSNK1DCSNK1E | |
| SCHEMBL2996833 | 0.72 | BRAF (0.35) | MEN1KMT2ADGAT2CSNK1DCSNK1E | |
| SCHEMBL2464199 | 0.72 | PPARG (0.34) | DGAT2CSNK1DCSNK1E | |
| SCHEMBL2994355 | 0.71 | BRAF (0.36) | CNR2DGAT2CSNK1DCSNK1E | |
| SCHEMBL2989353 | 0.71 | BRAF (0.46) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331502-B1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL MYERS SQUIBB CO (US) | 2016-03-02 | — | — | EP | disclosed |