Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL481123 | 0.84 | EPHX1 (0.36) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL1755702 | 0.80 | PTGER4 (0.40) | PTGER4DHFRCA12CA1CA2 | |
| SCHEMBL480790 | 0.79 | TACR1 (0.38) | PTGER4KMT2AEPHX1 | |
| SCHEMBL3105113 | 0.79 | TACR1 (0.38) | PTGER4KMT2AEPHX1 | |
| SCHEMBL481226 | 0.79 | PTGER4 (0.34) | PTGER4 | |
| SCHEMBL3105126 | 0.79 | TACR1 (0.38) | PTGER4KMT2AEPHX1 | |
| SCHEMBL481350 | 0.77 | AR (0.39) | PTGER4ALDH1A1NPC1RAB9A | |
| SCHEMBL29167883 | 0.74 | SLC6A3 (0.44) | PTGER4MEN1KMT2ASLC6A3 | |
| SCHEMBL16334384 | 0.72 | NPC1 (0.42) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL2830733 | 0.72 | ICAM1 (0.44) | DHFRMEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441762-A1 | Potentiators of Glutamate Receptors | Eli Lilly and Company (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2006057870-A1 | POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |