Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL481367 | 0.82 | PPARG (0.37) | PPARGPPARDPPARACYSLTR1CYSLTR2 | |
| SCHEMBL481366 | 0.82 | PPARG (0.37) | PPARGPPARDPPARACYSLTR1CYSLTR2 | |
| SCHEMBL13108325 | 0.79 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2GRM2 | |
| SCHEMBL1755735 | 0.78 | CYSLTR1 (0.41) | CYSLTR1CYSLTR2GRM2PDE5AMAPT | |
| SCHEMBL481234 | 0.77 | CYSLTR1 (0.41) | PPARGPPARDPPARACYSLTR1CYSLTR2 | |
| SCHEMBL481262 | 0.77 | CYSLTR1 (0.41) | PPARGPPARDPPARACYSLTR1CYSLTR2 | |
| SCHEMBL8263462 | 0.76 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2GRM2MEN1PDE5A | |
| SCHEMBL481143 | 0.74 | CYSLTR1 (0.45) | PPARGPPARDPPARACYSLTR1CYSLTR2 | |
| SCHEMBL1755709 | 0.73 | MAPT (0.41) | CYSLTR1CYSLTR2GRM2MEN1MAPT | |
| SCHEMBL1755775 | 0.73 | MAPT (0.41) | CYSLTR1CYSLTR2GRM2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441762-A1 | Potentiators of Glutamate Receptors | Eli Lilly and Company (US) | 2012-04-18 | — | — | EP | disclosed |