Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8265898 | 0.91 | CTSD (0.45) | CYSLTR1CYSLTR2CTSDGRM2LTB4R | |
| SCHEMBL481229 | 0.90 | CYSLTR1 (0.44) | CYSLTR1CYSLTR2CTSDGRM2LTB4R | |
| SCHEMBL481142 | 0.89 | CYSLTR1 (0.42) | CYSLTR1CYSLTR2CTSDGRM2LTB4R | |
| SCHEMBL481094 | 0.88 | CYSLTR1 (0.44) | CYSLTR1CYSLTR2CTSDGRM2LTB4R | |
| SCHEMBL1755706 | 0.87 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2CTSDGRM2LTB4R | |
| SCHEMBL480960 | 0.86 | CYSLTR1 (0.41) | CYSLTR1CYSLTR2CTSDGRM2LTB4R | |
| SCHEMBL481110 | 0.86 | CYSLTR1 (0.41) | CYSLTR1CYSLTR2CTSDGRM2LTB4R | |
| SCHEMBL481296 | 0.86 | CYSLTR1 (0.42) | CYSLTR1CYSLTR2CTSDGRM2LTB4R | |
| SCHEMBL481148 | 0.82 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2GRM2 | |
| SCHEMBL3095440 | 0.81 | CYSLTR1 (0.42) | CYSLTR1CYSLTR2CTSDGRM2LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441762-A1 | Potentiators of Glutamate Receptors | Eli Lilly and Company (US) | 2012-04-18 | — | — | EP | disclosed |