SCHEMBL17558136

SCHEMBL17558136

CCCCC/C=C\C/C=C\CCCCCCCCOc1ccc(OCCCCCCCC/C=C\C/C=C\CCCCC)c(C=O)c1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 1/20 0.43
TRPV1 Q8NER1 1/20 0.43
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
PPARA Q07869 1/20 0.42
PLA2G4B P0C869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17558137 1.00 TUBB1 (0.43) TUBB1TRPV1CNR1CNR2PPARA
SCHEMBL17558112 0.91 MAOB (0.46) TRPV1CNR1CNR2PPARAPLA2G4B
SCHEMBL17558110 0.91 MAOB (0.46) TRPV1CNR1CNR2PPARAPLA2G4B
SCHEMBL19376406 0.90 MGLL (0.52) CNR1CNR2PPARA
SCHEMBL17558124 0.90 MGLL (0.52) CNR1CNR2PPARA
SCHEMBL19399340 0.90 MAOB (0.45) TRPV1CNR1CNR2PPARAPLA2G4B
SCHEMBL19399339 0.88 MGLL (0.52) CNR1PPARA
SCHEMBL1790721 0.86 TUBB1 (0.50) TUBB1
SCHEMBL17577604 0.85 CNR1 (0.48) CNR1CNR2PPARAPLA2G4B
SCHEMBL5885093 0.83 TUBB1 (0.59) TUBB1PLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3188760-B1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2023-12-06 EP disclosed
US-10844002-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2020-11-24 US disclosed
US-10844002-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2020-11-24 US disclosed
US-20190002393-A1 Lipids and Lipid Compositions for the Delivery of Active Agents NOVARTIS AG (CH) 2019-01-03 US disclosed
US-20190002393-A1 Lipids and Lipid Compositions for the Delivery of Active Agents NOVARTIS AG (CH) 2019-01-03 US disclosed
US-10125092-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2018-11-13 US disclosed
US-20170275243-A1 Lipids and Lipid Compositions for the Delivery of Active Agents NOVARTIS AG (CH) 2017-09-28 US disclosed
US-20170275243-A1 Lipids and Lipid Compositions for the Delivery of Active Agents NOVARTIS AG (CH) 2017-09-28 US disclosed
US-20170275243-A1 Lipids and Lipid Compositions for the Delivery of Active Agents NOVARTIS AG (CH) 2017-09-28 US disclosed
EP-3188760-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS Novartis AG (CH) 2017-07-12 EP disclosed
WO-2016037053-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2016-03-10 WO disclosed
WO-2016037053-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2016-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10844002-B2 Lipids and lipid compositions for the delivery of active agents LRAT, LIPA, LPAR1 TUBB1 4265/4885TRPV1 2027/4885CNR1 1487/4885
US-20170275243-A1 Lipids and Lipid Compositions for the Delivery of Active Agents LRAT, LPAR4, LPAR1 TUBB1 4321/4885TRPV1 1961/4885CNR1 1519/4885
US-10125092-B2 Lipids and lipid compositions for the delivery of active agents LRAT, LPAR4, LPAR1 TUBB1 4321/4885TRPV1 1961/4885CNR1 1519/4885
US-20190002393-A1 Lipids and Lipid Compositions for the Delivery of Active Agents LRAT, LIPA, LPAR1 TUBB1 4265/4885TRPV1 2027/4885CNR1 1487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.