SCHEMBL175592

SCHEMBL175592

COc1cc(-c2nc(-c3ccc(N(C)C)cc3)c(-c3ccc(N(C)C)cc3)[nH]2)cc(OC)c1O

nearest known ligand 0.75

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMPD3 Q9NY59 10/20 0.75
NOX1 Q9Y5S8 4/20 0.73
MAPT P10636 5/20 0.67
TP53 P04637 3/20 0.67
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
KDM4E B2RXH2 1/20 0.56
ALDH1A1 P00352 1/20 0.56
GAA P10253 1/20 0.56
HPGD P15428 1/20 0.56
USP2 O75604 1/20 0.54
LMNA P02545 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
ALOX5 P09917 1/20 0.53
THRB P10828 1/20 0.50
MPO P05164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9648176 0.99 SMPD3 (0.73) SMPD3NOX1MAPTTP53MEN1
SCHEMBL9425683 0.95 SMPD3 (0.82) SMPD3NOX1MAPTTP53MEN1
SCHEMBL11613918 0.92 MAPT (0.64) SMPD3NOX1MAPTTP53MEN1
SCHEMBL12103550 0.90 SMPD3 (0.61) SMPD3NOX1MAPTTP53MEN1
SCHEMBL5676205 0.89 NOX1 (0.76) SMPD3NOX1MAPTTP53ALOX5
SCHEMBL9331183 0.88 SMPD3 (0.73) SMPD3NOX1MAPTTP53MEN1
SCHEMBL14445674 0.87 MAPT (0.59) SMPD3NOX1MAPTTP53MEN1
SCHEMBL9684940 0.87 SMPD3 (0.70) SMPD3NOX1MAPTTP53MEN1
Hydrochloric Acid SCHEMBL1735170 0.86 SMPD3 (0.71) SMPD3NOX1MAPTTP53MEN1
SCHEMBL9846824 0.86 SMPD3 (0.77) SMPD3NOX1MAPTTP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036472-A Photocatalysis preparation method of milbelin intermediate 山东新时代药业有限公司 2026-05-15 CN claimed
CN-119613996-A Functional melamine resin optical coating cured by sunlight and preparation method thereof 中科检测技术服务(重庆)有限公司 2025-03-14 CN claimed
CN-114667097-A Glycated hemoglobin measurement 奥索临床诊断有限公司 2022-06-24 CN claimed
CN-110172496-A A kind of Multilayer film dry plate for surveying hdl concentration 北京石油化工学院 2019-08-27 CN claimed
EP-1505393-B1 Dry analytical element for high-density lipoprotein cholesterol quantification ORTHO CLINICAL DIAGNOSTICS INC (US) 2014-12-31 EP claimed
US-20050032141-A1 Dry analytical element for high-density lipoprotein cholesterol quantification ORTHO-CLINICAL DIAGNOSTICS, INC. 2005-02-10 US claimed
EP-1505393-A1 Dry analytical element for high-density lipoprotein cholesterol quantification Ortho-Clinical Diagnostics, Inc. (US) 2005-02-09 EP claimed
EP-0699908-B1 Immunoassay elements having stable leuco dye coatings JOHNSON & JOHNSON CLIN DIAG (US) 2000-11-22 EP claimed
EP-0699905-B1 Leuco dye coating compositions JOHNSON & JOHNSON CLIN DIAG (US) 2000-05-17 EP claimed
US-5506116-A MIXING WITH NADH, TYROSINASE AND DYE, COLORIMETRIC ANALYSIS JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-04-09 US claimed
EP-0347139-A2 Imidazole leuco dye composition containing 4'-hydroxyacetanilide diagnostic kit and method using same EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-12-20 EP claimed
US-4828983-A INTERMEDIATES OF HIGHER OXIDATION POTENTIAL EASTMAN KODAK COMPANY (US) 1989-05-09 US claimed
US-4788140-A OPTICAL DENSITY, FILTER DYE EASTMAN KODAK COMPANY (US) 1988-11-29 US claimed
US-4591553-A Process and analytical agent for the determination of the activity of glutamate-oxalacetate-transaminase BOEHRINGER MANNHEIM GMBH (DE) 1986-05-27 US claimed
EP-0100413-B1 METHOD AND PREPARATION FOR THE DETERMINATION OF GLUTAMIC-OXALACETIC TRANSAMINASE ACTIVITY Roche Diagnostics GmbH (DE) 1986-02-05 EP claimed
US-RE32016-E A LACTASE OXIDASE, A SUBSTANCE HAVING PEROXIDATIVE ACTIVE, AND A MATERIAL THAT UNDERGOES DETECTABLE CHANGE EASTMAN KODAK COMPANY (US) 1985-10-29 US claimed
EP-0100413-A1 Method and preparation for the determination of glutamic-oxalacetic transaminase activity Roche Diagnostics GmbH (DE) 1984-02-15 EP claimed
US-4283491-A ADDITION COPOLYMERS FOR IMPROVED STORAGE OR PEROXIDASE REAGENT EASTMAN KODAK COMPANY (US) 1981-08-11 US claimed
US-4184923-A OXIDIZING ENZYME; PEROXIDASE; INDICATOR AND SOLVENT FOR SAME EASTMAN KODAK COMPANY (US) 1980-01-22 US claimed
US-4166763-A BY MEASURING AMOUNT OF HYDROGEN PEROXIDE PRODUCED EASTMAN KODAK COMPANY (US) 1979-09-04 US claimed